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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Determinants of cord blood adipokines and association with neonatal abdominal adipose tissue distribution
Karen Mei Ling Tan, Mya Thway Tint, Navin Michael, Fabian Yap, Yap-Seng Chong, Kok Hian Tan, Keith Godfrey, Anis Larbi, Yung Seng Lee, Shiao-Yng Chan, Marielle V. Fortier, Johan G. Eriksson & Neerja Karnani, 2021, International Journal of Obesity
DOI: 10.1038/s41366-021-00975-3
Type: article
Epigenome-wide association study of sarcopenia
Elie Antoun, Emma Garratt, Andrea Taddei, Mark Burton, Sheila Barton, Philip Titcombe, Leo Westbury, Alicia Baczynska, Eugenia Migliavacca, Jerome N. Feige, Holly Emma Syddall, Elaine Dennison, Richard Dodds, Helen Roberts, Peter Richardson, Avan A. Sayer, Sarah Shaw, Cyrus Cooper, Joanna D. Holbrook, Harnish Patel, Keith Godfrey & Karen Lillycrop, 2021, Journal of Cachexia, Sarcopenia and Muscle, 13(1), 240 - 253
DOI: 10.1002/jcsm.12876
Type: article
Analyses of child cardiometabolic phenotype following assisted reproductive technologies using a pragmatic trial emulation approach
Jonathan Y. Huang, Shirong Cai, Zhongwei Huang, Tint Mya, Wen Lun Yuan, Izzuddin M. Aris, Keith Godfrey, Neerja Karmani, Yung Seng Lee, Jerry Kok Yen Chan, Yap-Seng Chong, Johan G. Eriksson & Shiao-Yng Chan, 2021, Nature Communications, 12(1)
DOI: 10.1038/s41467-021-25899-4
Type: article
Combined analysis of gestational diabetes and maternal weight status from pre-pregnancy through post-delivery in future development of type 2 diabetes
Ling-Wei Chen, Shu-E. Soh, Mya Thway Tint, See Ling Loy, Fabian Yap, Kok Hian Tan, Yung Seng Lee, Lynette Pei-Chi Shek , Keith Godfrey, Peter D. Gluckman, Johan G. Eriksson, Yap-Seng Chong & Shiao-Yng Chan, 2021, Scientific Reports, 11(1)
DOI: 10.1038/s41598-021-82789-x
Type: article
Modifiable early life exposures associated with adiposity and obesity in 3-year old children born to mothers with obesity
Kathryn V. Dalrymple, Angela Flynn, Paul T. Seed, Annette Briley, Majella O’Keeffe, Keith Godfrey & Lucilla Poston, 2021, Pediatric Obesity, 16(11)
DOI: 10.1111/ijpo.12801
Type: article