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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researchers

Emeritus Professor Mark Hanson

Research interests
  • Developmental Origins of Health and Disease (DOHaD)
  • Maternal and Child Health
  • Developmental nutrition and epigenetic mechanisms
Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology
Research interests
  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hi…
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone miner…
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Automated segmentation of visceral, deep subcutaneous, and superficial subcutaneous adipose tissue volumes in MRI of neonates and young children
Yeshe Manuel Kway BEng, Kashthuri Thirumurugan, Mya Thway Tint, Navin Michael, Lynette Pei-Chi Shek , Fabian Yap, Kok Hian Tan, Keith Godfrey, Yap-Seng Chong, Marielle V. Fortier, Ute C. Marx, Johan G. Eriksson, Yung Seng Lee, Sendhil Velan, Mengling Feng & Suresh Anand Sadananthan, 2021, Radiology: Artificial Intelligence, 3(5)
DOI: 10.1148/ryai.2021200304
Type: article
Influence of maternal lifestyle and diet on perinatal DNA methylation signatures associated with childhood arterial stiffness at 8 to 9 years
Robert Murray, Negusse Kitaba, Elie Antoun, Philip Titcombe, Sheila Barton, Cyrus Cooper, Hazel M. Inskip, Graham C. Burdge, Pamela A. Mahon, John Deanfield, Julian P. Halcox, Elizabeth A. Ellins, Jennifer Bryant, Charles Peebles, Karen Lillycrop, Keith M. Godfrey, Mark A. Hanson & Epi Gen Consortium, 2021, Hypertension, 78(3), 787-800
DOI: 10.1161/HYPERTENSIONAHA.121.17396
Type: article
Placental polar lipid composition is associated with placental gene expression and neonatal body composition
Olaf Uhl, Rohan Lewis, Birgit Hirschmugl, Sarah Crozier, Hazel Inskip, Antonio Gázquez, Nicholas Harvey, Cyrus Cooper, Gernot Desoye, Berthold Koletzko, Christian Wadsack, Hans Demmelmair & Keith Godfrey, 2021, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1866(9)
DOI: 10.1016/j.bbalip.2021.158971
Type: article
Sequential assessment of bowel function and anorectal physiology after anterior resection for cancer
S A Pilkington, Rahul Bhome, Sally Gilbert, S Harris, Carl Richardson, T C Dudding, J S Knight, A T King, A H Mirnezami, N E Beck, P H Nichols & K P Nugent, 2021, Colorectal Disease, 23(9), 2436-2446
DOI: 10.1111/codi.15754
Type: article
Trajectories of systolic blood pressure in children: risk factors and cardiometabolic correlates
Wen Lun Yuan, Michael S. Kramer, Navin Michael, Suresh Sadananthan, Tint Mya, Ling-Wei Chen, Wei Wei Pang, Sendhil Velan, Keith Godfrey, Yap-Seng Chong, Mary Foong-Fong Chong, Jonathan TL Choo, L.H. Ling, Johan G. Eriksson & Yung Seng Lee, 2021, Journal of Pediatrics, 236, 86-94.e6
DOI: 10.1016/j.jpeds.2021.05.027
Type: article
Increasing nausea and vomiting of pregnancy is associated with sex-dependent differences in early childhood growth: the GUSTO Mother-Offspring Cohort Study
Judith Ong, Suresh Sadananthan, Shu-E Soh, Sharon Ng, Wen Lun Yuan, I.M. Aris, Mya Thway Tint, Navin Michael, See Ling Loy, Kok Hian Tan, Keith Godfrey, Lynette Shek, Fabian Yap, Yung Seng Lee, Yap-Seng Chong & Shiao-Yng Chan, 2021, BMC Pregnancy and Childbirth, 21(1)
DOI: 10.1186/s12884-021-04024-9
Type: article
Maternal Height, Gestational Diabetes Mellitus and Pregnancy Complications.
Anne H.Y. Chu, Wen Lun Yuan, See Ling Loy, Shu-E. Soh, Jonathan Y. Bernard, Mya Thway Tint, Sarah S T Ho-Lim, Huecin Goh, Adaikalavan Ramasamy, Mukkesh Kumar, Claire Goh, Li Ting Ang, Lynette Pei-Chi Shek , Yap-Seng Chong, Kok Hian Tan, Lin Lin Su, Arijit Biswas, Fabian Yap, Yung Seng Lee, Claudia Chi, Keith Godfrey, Johan G. Eriksson & Shiao-Yng Chan, 2021, Diabetes Research and Clinical Practice, 178
DOI: 10.1016/j.diabres.2021.108978
Type: article