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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Myo-inositol – a potential prophylaxis against premature onset of labour and preterm birth
Neha Sharma, Oliver C. Watkins, Anne H.Y. Chu, Wayne Cutfield, Keith Godfrey, Hannah E.J. Yong & Shiao-Yng Chan, 2021, Nutrition Research Reviews
DOI: 10.1017/S0954422421000299
Type: article
The association of maternal gestational hyperglycemia with breastfeeding duration and markers of milk production
Wei Wei Pang, Donna T. Geddes, Ching-Tat Lai, Shiao-Yng Chan, Yiong Huak Chan, Clara Y. Cheong, Doris Fok, Mei Chien Chua, Sok Bee Lim, Jonathan Y. Huang, Shikha Pundir, Kok Hian Tan, Fabian Yap, Keith Godfrey, Peter D. Gluckman, Lynette P. Shek, Mark H. Vickers, Johan G. Eriksson, Yap-Seng Chong & Mary E. Wlodek, 2021, American Journal of Clinical Nutrition, 114(3), 1219-1228
DOI: 10.1093/ajcn/nqab142
Type: article
Atopic dermatitis trajectories to age 8 years in the GUSTO cohort.
Noor H. A. Suaini, Gaik Chin Yap, Bui Do Phuong Tung, Evelyn X.L. Loo, Anne Eng Neo Goh, Oon Hoe Teoh, Kok Hian Tan, Keith Godfrey, Bee Wah Lee, Lynette Pei-Chi Shek , Hugo van Bever, Yap-Seng Chong & Elizabeth Huiwen Tham, 2021, Clinical & Experimental Allergy, 51(9), 1195-1206
DOI: 10.1111/cea.13993
Type: article
Automated segmentation of visceral, deep subcutaneous, and superficial subcutaneous adipose tissue volumes in MRI of neonates and young children
Yeshe Manuel Kway BEng, Kashthuri Thirumurugan, Mya Thway Tint, Navin Michael, Lynette Pei-Chi Shek , Fabian Yap, Kok Hian Tan, Keith Godfrey, Yap-Seng Chong, Marielle V. Fortier, Ute C. Marx, Johan G. Eriksson, Yung Seng Lee, Sendhil Velan, Mengling Feng & Suresh Anand Sadananthan, 2021, Radiology: Artificial Intelligence, 3(5)
DOI: 10.1148/ryai.2021200304
Type: article
Influence of maternal lifestyle and diet on perinatal DNA methylation signatures associated with childhood arterial stiffness at 8 to 9 years
Robert Murray, Negusse Kitaba, Elie Antoun, Philip Titcombe, Sheila Barton, Cyrus Cooper, Hazel M. Inskip, Graham C. Burdge, Pamela A. Mahon, John Deanfield, Julian P. Halcox, Elizabeth A. Ellins, Jennifer Bryant, Charles Peebles, Karen Lillycrop, Keith M. Godfrey, Mark A. Hanson & Epi Gen Consortium, 2021, Hypertension, 78(3), 787-800
DOI: 10.1161/HYPERTENSIONAHA.121.17396
Type: article