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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake
Elie Antoun, Philip Titcombe, Kathryn V. Dalrymple, Negusse Kitaba, Sheila Barton, A.C. Flynn, Robert Murray, Emma Garratt, Paul T. Seed, Sara L. White, Cyrus Cooper, Hazel Inskip, Mark Hanson, L. Poston, Keith Godfrey & Karen Lillycrop, 2021, Epigenetics
DOI: 10.1080/15592294.2021.1908706
Type: article
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors
R.C. Huang, P.E. Melton, M.A. Burton, L.J. Beilin, R. Clarke-Harris, E. Cook, K.M. Godfrey, G.C. Burdge, T.A. Mori, D Anderson , S. Rauschert, J.M. Craig, M.S. Kobor, J.L. MacIsaac, A.M. Morin, W.H. Oddy, C.E. Pennell, J.D. Holbrook & K.A. Lillycrop, 2021, Epigenetics
DOI: 10.1080/15592294.2021.1876297
Type: article
Gestational diabetes mellitus and developmental programming
Anne H.Y. Chu & Keith Godfrey, 2021, Annals of Nutrition and Metabolism
DOI: 10.1159/000509902
Type: article
Post-COVID economic recovery: women and children first ...or last?
Neena Modi, Gabriella Conti & Mark Hanson, 2021, Archives of Disease in Childhood, 0, 1-2
DOI: 10.1136/archdischild-2020-320898
Type: letterEditorial
Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight
N. Robinson, H. Brown, Elie Antoun, Keith Godfrey, Mark Hanson, Karen Lillycrop, Sarah Crozier, Robert Murray, M.S. Pearce, C.L. Relton, V. Albani & J.A. McKay, 2021, Clinical Epigenetics, 13(1)
DOI: 10.1186/s13148-020-00952-z
Type: article