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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Placental inositol reduced in gestational diabetes as glucose alters inositol transporters and IMPA1 enzyme expression
Reshma Appukuttan Pillai, Mohammed Omedul Islam, Preben Selvam, Neha Sharma, Anne HY Chu, Oliver C. Watkins, Keith Godfrey, Rohan Lewis & Shiao-Yng Chan, 2020, Journal of Clinical Endocrinology & Metabolism, 106(2), e875–e890
DOI: 10.1210/clinem/dgaa814
Type: article
Anthropocene-related disease: The inevitable outcome of progressive niche modification
Peter D. Gluckman, Felicia M. Low & Mark A. Hanson, 2020, Evolution, Medicine, and Public Health, 2020(1), 304-310
DOI: 10.1093/emph/eoaa042
Type: letterEditorial
Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial
Elie Antoun, Negusse T. Kitaba, Philip Titcombe, Kathryn V. Dalrymple, Emma S. Garratt, Sheila J. Barton, Robert Murray, Paul T. Seed, Joanna D. Holbrook, Michael S. Kobor, David Ts Lin, Julia L. Macisaac, Graham C. Burdge, Sara L. White, Lucilla Poston, Keith M. Godfrey & Karen A. Lillycrop, 2020, PLoS Medicine, 17(11)
DOI: 10.1371/journal.pmed.1003229
Type: article
Change in modifiable maternal characteristics and behaviours between consecutive pregnancies and offspring adiposity: a systematic review
Elizabeth Taylor, Sam Wilding, Nida Ziauddeen, Keith Godfrey, Ann Berrington & Nisreen Alwan, 2020, Obesity Reviews, 21(11)
DOI: 10.1111/obr.13048
Type: article
The effects of different smoking patterns in pregnancy on perinatal outcomes in the Southampton Women’s Survey
Martin O'Donnell, Janis Baird, Cyrus Cooper, Sarah Crozier, Keith Godfrey, Michael Geary , Hazel Inskip & Catherine B. Hayes, 2020, International Journal of Environmental Research and Public Health, 17(21), 7991
DOI: 10.3390/ijerph17217991
Type: article