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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation
Ling-Wei Chen, Jia Xu, S.E. Soh, I.M. Aris, Tint Mya, Peter D. Gluckman, Kok Hian Tan, Lynette P. Shek, Yap-Seng Chong, Fabian Yap, Keith Godfrey, Jack A. Gilbert, Neerja Karnani & Yung Seng Lee, 2020, International Journal of Obesity, 44(7), 1508-1520
DOI: 10.1038/s41366-020-0572-0
Type: article
Is breastfeeding associated with later child eating behaviours?
Wei Wei Pang, K. McCrickerd, Phaik Ling Quah, Anna Fogel, Izzuddin M. Aris, Wen Lun Yuan, Doris Fok, Mei Chien Chua, Sok Bee Lim, Lynette P. Shek, Shiao-Yng Chan, Kok Hian Tan, Fabian Yap, Keith Godfrey, Michael J. Meaney, Mary E. Wlodek, Johan Eriksson, Michael S. Kramer, Ciaran G Forde, Mary F.F. Chong & Yap-Seng Chong, 2020, Appetite, 150
DOI: 10.1016/j.appet.2020.104653
Type: article
Maternal glycemia during pregnancy and child carotid intima media thickness, pulse wave velocity, and augmentation index
Wen Lun Yuan, J. Lin, Michael S. Kramer, Keith Godfrey, Peter D. Gluckman, Yap-Seng Chong, Lynette P. Shek, Kok Hian Tan, Shiao-Yng Chan, Johan G. Eriksson, Fabian Yap, Yung Seng Lee, Jonathan T.L. Choo & L.H. Ling, 2020, Journal of Clinical Endocrinology & Metabolism, 105(7), 1-10
DOI: 10.1210/clinem/dgaa211
Type: article
Maternal glycemia during pregnancy and offspring abdominal adiposity measured by MRI in the neonatal period and preschool years: The Growing Up in Singapore Towards healthy Outcomes (GUSTO) prospective mother-offspring birth cohort study
Tint Mya, Suresh Sadananthan, Shu-E Soh, Izzuddin M. Aris, Navin Michael, Kok H. Tan, Lynette P. Shek, Fabian Yap, Peter D. Gluckman, Y-S Chong, Keith Godfrey, Sendhil Velan, Shiao-Yng Chan, Johan G. Eriksson, Marielle V. Fortier, Cuilin Zhang & Yung Seng Lee, 2020, American Journal of Clinical Nutrition, 112(1), 39-47
DOI: 10.1093/ajcn/nqaa055
Type: article
Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy
Luiza Borges Manna, Georgia Papacleovoulou, Flavia Flaviani, Vanessa Formigo-Pataia, Asaad Qadri, Shadi Abu-Hayyeh, Saraid Mcilvride, Eugene Jansen, Peter Dixon, Jennifer Chambers, Marta Vazquez Lopez, Annika Wahlstroem, Negusse Kitaba, Hanns-Ulrich Marschall, Keith Godfrey, Karen Lillycrop & Catherine Williamson, 2020, Scientific Reports, 10(1)
DOI: 10.1038/s41598-020-67301-1
Type: article