Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases

Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics

Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC

Research interests

Joanne has research interests in health economic evaluation and decision modelling.
She has worked on a wide range of applied cost-effectiveness studies, including:
a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.

Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Southampton Health Technology Assessments Centre

We are a leading centre for health technology assessment and health services research in the UK. Our expertise in evidence synthesis, health economics and information science informs timely policy decisions on the use of new healthcare technology and services, directly benefitting patients and ensuring good value for money for our health service.

Research outputs

Pragmatic multicentre randomised controlled trial evaluating the impact of a routine molecular Point-of-Care ‘test-and-treat’ strategy for influenza in adults hospitalised with acute respiratory illness (FluPOC): trial protocol

Kate Beard, Nathan Brendish, Ahalya K Malachira, Samuel Mills, Cathleen Chan , Stephen Poole & Tristan Clark, 2019, BMJ Open, 9(12)

DOI: 10.1136/bmjopen-2019-031674

Type: article

Feasibility of Point-of-Care testing for influenza within a national primary care sentinel surveillance network in England: protocol for a mixed methods study

Tristan Clark, Simon de Lusignan, Uy Hoang, Harshana Liyanage, Ivelina Yonova, Filipa Ferreira & Javier Diez-Domingo, 2019, JMIR Research Protocols, 8(11)

DOI: 10.2196/14186

Type: article

Impact of point-of-care testing for respiratory viruses on antibiotic use in adults with exacerbation of airways disease

Nathan Brendish, Samuel Mills, Sean Ewings & Tristan Clark, 2019, Journal of Infection, 79(4), 357-362

DOI: 10.1016/j.jinf.2019.06.010

Type: article

Molecular point-of-care testing for influenza to improve early neuraminidase inhibitor treatment and outcomes in hospitalised adults

Nathan Brendish & Tristan W. Clark, 2019, Clinical Infectious Diseases, 68(12), 2154-2155

DOI: 10.1093/cid/ciy1042

Type: letterEditorial

Hospitalised adults with pneumonia are frequently misclassified as another diagnosis

Nathan Brendish, Ahalya Malachira, Kate Beard, Lawrence Armstrong, Patrick J. Lillie & Tristan Clark, 2019, Respiratory Medicine, 150, 81-84