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Research project

Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases
Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC

Research interests

  • Joanne has research interests in health economic evaluation and decision modelling.
  • She has worked on a wide range of applied cost-effectiveness studies, including:
  • a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.
Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Neuraminidase inhibitor use in adults presenting to hospital with suspected influenza: a questionnaire-based survey of practice among hospital physicians
Nathan Brendish, Ahalya K Malachira, Patrick J Lillie & Tristan Clark, 2021, Clinical Infection in Practice, 11
DOI: 10.1016/j.clinpr.2021.100075
Type: article
Comparison of serological assays for the detection of SARS-CoV-2 antibodies
Joe James, Shelley Rhodes, Craig Ross, Paul Skinner, Samuel Smith, Rebecca Shipley, Caroline Warren, Hooman Goharriz, Lorraine McElhinney, Nigel Templeton, Edward Wright, Anthony Fooks, Tristan Clark, Sharon Brookes, Ian Brown & Ashley Banyard, 2021, Viruses, 13(4), 713
DOI: 10.3390/v13040713
Type: article
Influenza vaccination: protecting the most vulnerable
Alex Tanner, Robert B. Dorey, Nathan Brendish & Tristan Clark, 2021, European Respiratory Review, 30(159)
DOI: 10.1183/16000617.0258-2020
Type: article
Using Point of Care Testing to estimate influenza vaccine effectiveness in the English primary care sentinel surveillance network
Tristan Clark, Simon de Lusignan, Uy Hoang, Harshana Liyanage, Manasa Tripathy, Julian Sherlock, Mark Joy, Filipa Ferreira & Javier Diez-Domingo, 2021, PLoS ONE, 16, 1-11
DOI: 10.1371/journal.pone.0248123
Type: article
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial
Phillip D Monk, Richard J Marsden, Victoria J Tear, Jody Brookes, Toby N Batten, Marcin Mankowski, Felicity J Gabbay, Donna E Davies, Stephen T Holgate, Ling-Pei Ho, Tristan Clark, Ratko Djukanovic, Tom M A Wilkinson, Michael G Crooks, Davinder P S Dosanjh, Salman Siddiqui, Najib M Rahman, Jacklyn A Smith, Alexander Horsley, Timothy W Harrison, Dinesh Saralaya, Lorcan McGarvey, Alastair Watson, Edmund Foster, Adam Fleet, Dave Singh, Sophie Hemmings, Sandra Aitken, Sarah Dudley, Rona Beegan, Angela Thompson & Pedro M B Rodrigues, 2021, The Lancet Respiratory Medicine, 9(2), 196-206
DOI: 10.1016/S2213-2600(20)30511-7
Type: article