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Research project

Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases
Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC

Research interests

  • Joanne has research interests in health economic evaluation and decision modelling.
  • She has worked on a wide range of applied cost-effectiveness studies, including:
  • a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.
Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department
Christopher Mansbridge, Alex Tanner, Kate Beard, Florina Borca, Hang Thi Thu Phan, Nathan Brendish, Stephen Poole, Christopher Hill, Michael Kuber, Robert Crouch, Waddington Daniel & Tristan Clark, 2022, Infection Control and Hospital Epidemiology, 43(8), 979-986
DOI: 10.1017/ice.2021.531
Type: article
Combined RT-PCR and host response point-of-care testing in patients hospitalised with suspected COVID-19: a prospective diagnostic accuracy study
Nathan Brendish, Alex Tanner, Stephen Poole, Kate Beard, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland & Tristan Clark, 2022, Infectious Diseases and Therapy, 11(3), 1267–1280
DOI: 10.1007/s40121-022-00646-4
Type: article
Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19
Robert Livingstone, Hlaing Lin, Nathan Brendish, Stephen Poole, Florina Borca, Alex Tanner, Trevor Smith , Matt Stammers & Tristan Clark, 2022, Journal of Infection, 84(4), 558-565
DOI: 10.1016/j.jinf.2022.01.034
Type: article
Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield
Tristan Clark, S Serigstat, D Markussen, Harleen Grewal, M Ebbesen, O Kommedal, L Heggelund, CH van Werkhoven, D Faurholt-Jepsen, C Ritz, E Ulvestad, R Bjorneklett & ST Knoop, 2022, Scientific Reports, 12(326)
DOI: 10.1038/s41598-021-03741-7
Type: article
A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries
Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie & Christopher Mccormick, 2022, Journal of Infection, 84(1), 48-55
DOI: 10.1016/j.jinf.2021.08.049
Type: article