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Research project

Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases
Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC

Research interests

  • Joanne has research interests in health economic evaluation and decision modelling.
  • She has worked on a wide range of applied cost-effectiveness studies, including:
  • a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.
Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Impact of rapid molecular testing on diagnosis, treatment and management of community-acquired pneumonia in Norway
Sondre Serigstad, Christian Ritz, Daniel Faurhold-Jepsen, Dagfinn Markussen, Marit Ebbeseb, Oyvind Kommedal, Lars Heggelund, Tristan Clark, Cornelis van Werkhoven, Siri Knoop, Elling Ulvestad & Harleen Grewal, 2022, Trials, 23(1)
DOI: 10.1186/s13063-022-06467-7
Type: article
Respiratory virus transmission using a novel viral challenge model: An observational cohort study
Marie-Jo Medina, Joshua Nazareth, Helen Dillon, Christopher Wighton, Srini Bandi, Daniel Pan, Karl Nicholson, Tristan Clark, Peter Andrews & Manish Pareek , 2022, Journal of Infection, 85(4), 405 - 411
DOI: 10.1016/j.jinf.2022.08.004
Type: article
The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemic.
Sondre Serigstad, Dagfnn Markussen, Christian Ritz, Marit H Ebbesen, Siri T Knoop, Øyvind Kommedal, lars Heggelund, Elling Ulvestad, Rune O. Bjørneklett, Harleen Grewal & Tristan Clark, 2022, BMC Infectious Diseases, 22(1)
DOI: 10.1186/s12879-022-07732-5
Type: article
Blood gene expression predicts intensive care unit admission in hospitalised patients with COVID-19
Rebekah Penrice-Randal, Xiaofeng Dong, Andrew George Shapanis, Aaron Gardner, Nicholas Harding, Jelmer Legebeke, Jenny Lord, Andres F Vallejo, Stephen Poole, Nathan J Brendish, Catherine Hartley, Anthony P Williams, Gabrielle Wheway, Marta E Polak, Fabio Strazzeri, James P R Schofield, Paul J Skipp, Julian A Hiscox, Tristan W Clark & Diana Baralle, 2022, Frontiers in Immunology, 13
DOI: 10.3389/fimmu.2022.988685
Type: article
Is the UK prepared for seasonal influenza in 2022–23 and beyond?
Tristan Clark, Joshua Nazareth, Daniel Pan, Christopher Martin, Ian Burr, Sheena Sullivan, Iain Stephenson, Laura Nellums, Amandeep Sahota, Julian Tang & Manish Pareek, 2022, The Lancet Infectious Diseases, 22(9), 1280 - 1281
DOI: 10.1016/S1473-3099(22)00503-5
Type: letterEditorial