About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Member of:
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Sponsor: Medical Research Council
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Wessex Medical Research
Publications
66 publications
Page 7 of 7
Martin Gengenbacher, Teresa B Fitzpatrick, Thomas Raschle, Karlheinz Flicker, Irmgard Sinning, Sylke Müller, Peter Macheroux, Ivo Tews & Barbara Kappes,
2006, The Journal of Biological Chemistry, 281(6), 3633-3641
Type: article
Claudia Seelenmeyer, Sabine Wegehingel, Ivo Tews, Markus Künzler, Markus Aebi & Walter Nickel,
2005, PLoS ONE, 171(2), 373-381
Type: article
Ivo Tews, Felix Findeisen, Irmgard Sinning, Anita Schultz, Joachim E Schultz & Jürgen U Linder,
2005, Science, 308(5724), 1020-1023
Type: article
Edward D Lowe, Ivo Tews, Kin Yip Cheng, Nick R Brown, Sheraz Gul, Martin E M Noble, Steven J Gamblin & Louise N Johnson,
2002, Biochemistry, 41(52), 15625-15634
DOI: 10.1021/bi0268910
Type: article
Ivo Tews, A. Perrakis, A. Oppenheim, Z. Dauter, K. S. Wilson & C. E. Vorgias,
1996, Nature Structural Biology, 3(7), 638-648
Type: article
A Perrakis, I Tews, Z Dauter, A B Oppenheim, I Chet, K S Wilson & C E Vorgias,
1994, Structure, 2(12), 1169-1180
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)