About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Member of:
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Sponsor: Medical Research Council
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Wessex Medical Research
Publications
66 publications
Page 3 of 7
Selina L S Storm, Adam D Crawshaw, Nicholas E Devenish, Rachel Bolton, David R Hall, Ivo Tews & Gwyndaf Evans,
2020, IUCrJ, 7(Part 1), 129-135
Type: article
John H. Beale, Rachel Bolton, Stephen A. Marshall, Emma V. Beale, Stephen B. Carr, Ali Ebrahim, Tadeo Moreno-Chicano, Michael A. Hough, Jonathan A.R. Worrall, Ivo Tews & Robin L. Owen,
2019, Journal of Applied Crystallography, 52(Pt 6), 1385-1396
Type: article
Maria Victoria Humbert, Alexandra Jackson, Christian M. Orr, Ivo Tews & Myron Christodoulides,
2019, Scientific Reports, 9(1), 1-14
Type: article
Greta Reintjes, Halina E. Tegetmeyer, Miriam Bürgisser, Sandi Orlić, Ivo Tews, Mikhail Zubkov, Daniela Voß, Oliver Zielinski, Christian Quast, Frank Oliver Glöckner, Rudolf Amann, Timothy G. Ferdelman & Bernhard M. Fuchs,
2019, Applied and Environmental Microbiology, 85(14), 1-14
DOI: 10.1128/AEM.00184-19
Type: article
Despo Polyviou, Moritz Machelett, Andrew Hitchcock, Alison Baylay, Fraser MacMillan, C. Mark Moore, Christopher Moore, Thomas Bibby & Ivo Tews,
2018, The Journal of Biological Chemistry, 293, 18099-18109
Type: article
Hannia, Liliana Almonacid Mendoza, Maria Humbert, Aiste Dijokaite, David Cleary, Yiwen Soo, Miao-chiu Hung, Christian M. Orr, Ivo Tews & Moritz M. Machelett,
2018, mSphere, 10(3), 1-25
Type: article
Emma, Jill Sutton, Richard Bradshaw, Christian Orr, Björn Frendéus, Gunilla Larsson, Ingrid Teige, Mark Cragg, Ivo Tews & Jonathan W. Essex,
2018, Biophysical Journal, 115(2), 289-299
Type: article
Xiaojie Yu, Hak Chan, Christian Orr, Osman Dadas, Steven Booth, Lekh Dahal, Christine Penfold, Lyn O'Brien, Christopher Mockridge, Ruth French, Patrick Duriez, Leon Douglas, Arwen R. Pearson, Mark Cragg, Ivo Tews, Martin Glennie & Ann L. White,
2018, Cancer Cell, 33(4), 664-675
Type: article
Andrew Chancellor, Anna Tocheva, Christopher Cave-Ayland, Liku Bekele Tezera, Andrew White, Juma'a Al Dulayymi, John Bridgeman, Ivo Tews, Susan Wilson, Nikolai Lissin, Marc Tebruegge, Benjamin Marshall, Sally Sharpe, Timothy Elliott, Chris-Kriton Skylaris, Jonathan W. Essex, Mark Baird, Stephan D. Gadola, Paul Elkington & Salah Mansour,
2017, Proceedings of the National Academy of Sciences, 114(51), E10956-E10964
Type: article
Matthew J. Rodrigues, Volker Windeisen, Yang Zhang, Gabriela Guédez, Stefan Weber, Marco Strohmeier, Jeremiah W. Hanes, Antoine Royant, Gwyndaf Evans, Irmgard Sinning, Steven E. Ealick, Tadhg P. Begley & Ivo Tews,
2017, Nature Chemical Biology, 13(3), 290-294
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)