Research project

R Carare - Physiology of Perivascular drainage of the brain and how it is affected by advancing age

Lead researchers:

Professor Roxi Carare
Other researchers:

Professor James Nicoll
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Lead researchers

Professor Roxi Carare

Head of School

Research interests

Causes and new therapeutic strategies for dementias and other neurodegenerative diseases
New early diagnostic measures in dementia based on biomarkers from the nose
Drug delivery to the brain

Connect with Roxi

Email: R.O.Carare@soton.ac.uk

Other researchers

Professor James Nicoll

Connect with James

Email: J.Nicoll@soton.ac.uk

Research outputs

Pathophysiology of lymphatic drainage of the central nervous system: implications for the pathophysiology of multiple sclerosis

Roy O. Weller, Roxanna O. Carare, Cheryl A. Hawkes & Ian Galea, 2015

DOI: 10.1016/B978-0-12-800763-1.00019-1

Type: bookChapter

Are you also what your mother eats? Distinct proteomic portrait as a result of maternal high-fat diet in the cerebral cortex of the adult mouse

A. Manousopoulou, J. Woo, C.H. Woelk, H. Johnston, A. Singhania, C. Hawkes, Spiros D. Garbis & Roxana-Octavia Carare, 2015, International Journal of Obesity, 39(8), 1325-1328

DOI: 10.1038/ijo.2015.35

Type: article

Prenatal high-fat diet alters the cerebrovasculature and clearance of beta-amyloid in adult offspring

Cheryl A. Hawkes, Steve M. Gentleman, James A.R. Nicoll & Roxana-Octavia Carare, 2015, The Journal of Pathology, 235(4), 619-631

DOI: 10.1002/path.4468

Type: article

Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy

Cheryl A Hawkes, Nimeshi Jayakody, David A Johnston, Ingo Bechmann & Roxana O Carare, 2014, Brain Pathology, 24(4), 396-403

DOI: 10.1111/bpa.12159

Type: article

Amyloid and tau in the brain in sporadic Alzheimer’s disease: defining the chicken and the egg

Cheryl A. Hawkes, Roxana O. Carare & Roy O. Weller, 2014, Acta Neuropathologica, 127(4), 617-618

DOI: 10.1007/s00401-014-1243-9

Type: article