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Research project

Long-lived Nuclear Hyperpolarization of Methyl Groups

Project overview

This project consists of the hyperpolarization of long-lived states in methyl groups and their isotopomers. The project makes use of solution NMR and dissolution-DNP equipment.

Staff

Lead researchers

Professor Malcolm Levitt

Professor of Chemistry

Research interests

  • Magnetic Resonance
  • Endofullerenes
Connect with Malcolm

Email: mhl@soton.ac.uk

Other researchers

Professor Richard Brown

Professor of Organic Chemistry

Research interests

  • Organic synthesis
  • Total synthesis of natural products
  • Asymmetric synthesis
Connect with Richard

Email: R.C.Brown@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

NMR of 133Cs+ in stretched hydrogels: one-dimensional, z- and NOESY spectra, and probing the ion’s environment in erythrocytes
Philip W. Kuchel, Dmitry Shishmarev, Max Puckeridge, Malcolm Levitt, Christoph Naumann & Bogdan E. Chapman, 2015, Journal of Magnetic Resonance, 261, 110-120
DOI: 10.1016/j.jmr.2015.10.011
Type: article
Symmetry constraints on spin dynamics: application to hyperpolarized NMR
Malcolm H. Levitt, 2015, Journal of Magnetic Resonance, 1-9
DOI: 10.1016/j.jmr.2015.08.021
Type: article
Letter. Synthesis of an isotopically labeled naphthalene derivative that supports a long-lived nuclear singlet state
Joseph Hill-Cousins, Ionut-Alexandru Pop, Giuseppe Pileio, Gabriele Stevanato, Par Hakansson, Soumya Singha Roy, Malcolm Levitt, Lynda Brown & Richard Brown, 2015, Organic Letters, 17(9), 2150-2153
DOI: 10.1021/acs.orglett.5b00744
Type: article
A nuclear singlet lifetime of more than one hour in room-temperature solution
Gabriele Stevanato, Joseph T. Hill-Cousins, Pär Håkansson, Soumya Singha Roy, Lynda J. Brown, Richard C.D. Brown, Giuseppe Pileio & Malcolm H. Levitt, 2015, Angewandte Chemie International Edition, 54(12), 3740-3743
DOI: 10.1002/anie.201411978
Type: article
Theory of long-lived nuclear spin states in methyl groups and quantum-rotor induced polarisation
Jean-Nicolas Dumez, Par Hakansson, Salvo Mamone, Benno Meier, Gabriele Stevanato, Joseph Hill-Cousins, Soumya Singha Roy, Richard Brown, Giuseppe Pileio & Malcolm Levitt, 2015, The Journal of Chemical Physics, 142(4), 1-13
DOI: 10.1063/1.4906273
Type: article