Research project

J Holloway: Trangenerational Epigenetic inheritance of allergy in a Multigenerational Cohort

Lead researchers:

Professor John Holloway
Research funder:

National Institutes of Health
Status:

Not active

Staff

Lead researchers

Professor John Holloway PhD, FHEA

Associate V-P Interdisciplinary Research

Research interests

Human genetics
Epigenetics
Respiratory Disease

Connect with John

Email: J.W.Holloway@soton.ac.uk

Research outputs

Evaluating the efficacy of breastfeeding guidelines on long-term outcomes for allergic disease

Victoria Bion, Gabrielle A. Lockett, Nelís Soto-Ramírez, Hongmei Zhang, Carina Venter, Wilfried Karmaus, John W. Holloway & S. Hasan Arshad, 2016, Allergy, 71(5), 661-670

DOI: 10.1111/all.12833

Type: article

DNA methylation and genetic polymorphisms of the Leptin gene interact to influence lung function outcomes and asthma at 18 years of age

Nadini Mukherjee, Gabrielle A. Lockett, Simon K. Merid, Eric Melén, Göran Pershagen, John Holloway, Syed Hasan Arshad, Susan Ewart, Hongmei Zhang & Wilfried Karmaus, 2016, International Journal of Molecular Epidemiology and Genetics, 7(1), 1-17

Type: article

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection

Todd M. Everson, Genevieve Lyons, Hongmei Zhang, Nelís Soto-Ramírez, Gabrielle A. Lockett, Veeresh, Keshirajagowda Patil, Simon K. Merid, Cilla Sӧderhӓll, Erik Melén, John W. Holloway, S. Hasan Arshad & Wilfried Karmaus, 2015, Genome Medicine, 7(1), 89

DOI: 10.1186/s13073-015-0213-8

Type: article

Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity

Veeresh K Patil, John W Holloway, Hongmei Zhang, Nelis Soto-Ramirez, Susan Ewart, S Hasan Arshad & Wilfried Karmaus, 2013, Clinical Epigenetics, 5(1), 1-6

DOI: 10.1186/1868-7083-5-22

Type: article

The methylation of the LEPR/LEPROT genotype at the promoter and body regions influence concentrations of leptin in girls and BMI at age 18 years if their mother smoked during pregnancy

Mitra Yousefi, Wilfried Karmaus, Hongmei Zhang, Susan Ewart, Hasan Arshad & John W Holloway, 2013, International Journal of Molecular Epidemiology and Genetics, 4(2), 86-100

Type: article