Research project

J Holloway: Trangenerational Epigenetic inheritance of allergy in a Multigenerational Cohort

Lead researchers:

Professor John Holloway
Research funder:

National Institutes of Health
Status:

Not active

Staff

Lead researchers

Professor John Holloway PhD, FHEA

Associate V-P Interdisciplinary Research

Research interests

Human genetics
Epigenetics
Respiratory Disease

Connect with John

Email: J.W.Holloway@soton.ac.uk

Research outputs

Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy

Ali H Ziyab, Susan Ewart, Gabrielle A Lockett, Hongmei Zhang, Syed Arshad, John W Holloway & Wilfried Karmaus, 2017, Clinical & Experimental Allergy, 47(9), 1185-1192

DOI: 10.1111/cea.12956

Type: article

The role of DNA methylation in type 2 diabetes aetiology – using genotype as a causal anchor

Hannah Elliot, Hashem Shihab, Gabrielle A. Lockett, John Holloway, Allan F. McRae, George Davey-Smith, Susan M. Ring, Tom R. Gaunt & Caroline L. Relton, 2017, Diabetes, 66(6), 1713-1722

DOI: 10.2337/db16-0874

Type: article

Multi-generational cohorts in asthma and allergy

Hasan Arshad, Wilfried Karmaus, Hongmei Zhang & John W. Holloway, 2017, Journal of Allergy and Clinical Immunology, 139(2), 415-421

DOI: 10.1016/j.jaci.2016.12.002

Type: article

Tetanus vaccination is associated with differential DNA-methylation: Reduces the risk of asthma in adolescence

Vimala Devi Janjanam, Nandini Mukherjee, Gabrielle A. Lockett, Faisal I. Rezwan, Ramesh Kurukulaaratchy, Frances Mitchell, Hongmei Zhang, Hasan Arshad, John Holloway & Wilfried Karmaus, 2016, Vaccine, 34(51), 6493-6501

DOI: 10.1016/j.vaccine.2016.10.068

Type: article

Is there an association between season of birth and blood DNA methylation in adulthood?

P-A. Dugué, Y. M. Geurts, R. L. Milne, G.A. Lockett, H. Zhang, W. Karmaus & J. W. Holloway, 2016, Allergy, 71(10), 1501-1504

DOI: 10.1111/all.12949

Type: article