Research project

High Resolution Solid State Nitrogen-14 NMR

Research groups:

Cell and Developmental Biology
Lead researchers:

Professor Marina Carravetta
Other researchers:

Professor Phil Williamson,

Professor Ilya Kuprov
Research funder:

EPSRC
Status:

Not active

Project overview

Solid state NMR spectroscopy of the major naturally occurring isotope of nitrogen will be made easier and more informative. This opens a new route to characterize biomolecules, natural materials, drugs, and proteins.

Staff

Lead researchers

Professor Marina Carravetta

Professor

Research interests

Solid state magic-angle spinning NMR
Quantum Technology for Magnetic Resonance
High temperature and/or high pressure NMR

Connect with Marina

Email: M.Carravetta@soton.ac.uk

Other researchers

Professor Phil Williamson

Head of School

Research interests

Molecular processes underpinning neurodegenerative disease
Structure and function of cell membranes
Development and application of solid-state NMR and other biophysical techniques for the analysis of biological systems

Connect with Phil

Email: P.T.Williamson@soton.ac.uk

Professor Ilya Kuprov FRSC

Professor of Physics

Connect with Ilya

Email: i.kuprov@soton.ac.uk

Collaborating research institutes, centres and groups

Magnetic Resonance

Our main focus is finding ways to extend the timescale over which magnetic resonance can be made.

Research outputs

Strategies for ¹H-Detected Dynamic Nuclear Polarization Magic-Angle Spinning NMR Spectroscopy

Maria Concistre, Subhradip Paul, Marina Carravetta, Ilya Kuprov & Philip Williamson, 2020, Chemistry - A European Journal, 26(68), 15852-15854

DOI: 10.1002/chem.202003463

Type: article

Quantitative analysis of Q2 14N quadrupolar coupling using 1H detected 14N solid-state NMR†

James Jarvis, Maria Concistre, Ibraheem Haies, Richard Bounds, Ilya Kuprov, Marina Carravetta & Philip Williamson, 2019, Physical Chemistry Chemical Physics, 21(11), 5941-5949

DOI: 10.1039/C8CP06276E

Type: article

14N overtone NMR under MAS

Maria Concistre, Ilya Kuprov, Ibraheem M. Haies, Philip Williamson & Marina Carravetta, 2019, Journal of Magnetic Resonance, 298, 1-5

DOI: 10.1016/j.jmr.2018.10.017

Type: article

Measurement of ¹⁴N Quadrupole Couplings in Biomolecular Solids Using Indirect-Detection ¹⁴N Solid-State NMR with DNP

James Jarvis, Ibraheem Haies, Moreno Lelli, Aaron Rossini, Ilya Kuprov, Marina Carravetta & Philip Williamson, 2017, Chemical Communications, 53(89), 12116-12119

DOI: 10.1039/c7cc03462h

Type: article

Bidirectional band-selective magnetization transfer along the protein backbone doubles the information content of solid-state NMR correlation experiments

M.M. Jolly, J.A. Jarvis, M. Carravetta, M.H. Levitt & P.T.F. Williamson, 2017, Journal of Biomolecular NMR

DOI: 10.1007/s10858-017-0147-0

Type: article