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Research project

J Nicoll art/pg2006/4

Staff

Lead researcher

Professor James Nicoll

Connect with James

Email: J.Nicoll@soton.ac.uk

Other researchers

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

  • Neuroimmunology and neurodegeneration
  • Immunophenotyping immune cells
  • Human brain pathology
Connect with Delphine

Email: D.Boche@soton.ac.uk

Emeritus Professor Clive Holmes

Connect with Clive

Email: C.Holmes@soton.ac.uk

Research outputs

Downregulated apoptosis and autophagy after anti-Aβ immunotherapy in Alzheimer’s disease
Claire Paquet, James Nicoll, Seth Love, François Mouton-Liger, Clive Holmes, Jacques Hugon & Delphine Boche, 2017, Brain Pathology
DOI: 10.1111/bpa.12567
Type: article
Effect of amyloid-β (Aβ) immunization on hyperphosphorylated tau: a potential role for glycogen synthase kinase (GSK)-3β
Jay Amin, Claire Paquet, Alex Baker, Ayodeji A. Asuni, Seth Love, Clive Holmes, Jacques Hugon, James A.R. Nicoll & Delphine Boche, 2015, Neuropathology and Applied Neurobiology, 41(4), 445-457
DOI: 10.1111/nan.12205
Type: article
Effect of active Abeta immunotherapy on neurons in human Alzheimer's disease
Claire Paquet, Jay Amin, François Mouton-Liger, Mariam Nasser, Seth Love, Françoise Gray, Ruth M. Pickering, James A.R. Nicoll, Clive Holmes, Jacques Hugon & Delphine Boche, 2015, The Journal of Pathology, 235(5), 721-730
DOI: 10.1002/path.4491
Type: article
Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy
Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love & James A R Nicoll, 2014, Acta Neuropathologica, 128(6), 777-789
DOI: 10.1007/s00401-014-1340-9
Type: article
Investigating interventions in Alzheimer's disease with computer simulation models
Carole J. Proctor, Delphine Boche, Douglas A. Gray & James A.R. Nicoll, 2013, PLoS ONE, 8(9), e73631
DOI: 10.1371/journal.pone.0073631
Type: article