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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Pregnancy trimester-specific exposure to ambient air pollution and child respiratory health outcomes in the first 2 years of life
Shu-E. Soh, Anne Goh, Oon Hoe Teoh, Keith M. Godfrey, Peter D. Gluckman, Lynette Pei-Chi Shek & Yap-Seng Chong, 2018, International Journal of Environmental Research and Public Health, 15(5)
DOI: 10.3390/ijerph15050996
Type: article
Origins of lifetime health around the time of conception
T.P. Fleming, A. Watkins, M.A. Velazquez, J. C. Mathers, A.M. Prentice, J. Stephenson, Mary Barker, R. Saffery, Chittaranjan S. Yajnik, Judith Eckert, Mark Hanson, T. Forrester, Peter D. Gluckman & Keith Godfrey, 2018, The Lancet, 391(10132), 1842–1852
DOI: 10.1016/S0140-6736(18)30312-X
Type: article
Epigenome-wide association study of adiposity and future risk of obesity-related diseases
Gianluca Campanella, Marc J. Gunter, Silvia Polidoro, Vittorio Krogh, Domenico Palli, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Giovanni Fiorito, Simonetta Guarrera, Licia Iacoviello, Ingvar A. Bergdahl, Beatrice Melin, Per Lenner, Theo M.C.M. de Kok, Panagiotis Georgiadis, Jos C.S. Kleinjans, Soterios A. Kyrtopoulos, H. Bas Bueno-de-Mesquita, Karen A. Lillycrop, Anne M. May, N. Charlotte Onland-Moret, Robert Murray, Elio Riboli, Monique Verschuren, Eiliv Lund, Nicolle Mode, Torkjel M. Sandanger, Valentina Fiano, Morena Trevisan, Giuseppe Matullo, Philippe Froguel, Paul Elliott, Paolo Vineis & Marc Chadeau-Hyam, 2018, International Journal of Obesity, 1-14
DOI: 10.1038/s41366-018-0064-7
Type: article
Maternal and fetal genetic contribution to gestational weight gain
Nicole M. Warrington, Rebecca Richmond, Bjarke Feenstra, Ronny Myhre, Romy Gaillard, Lavinia Paternoster, Carol A. Wang, Robin N Beaumont, Shikta Das, Mario Murcia, Sheila Barton, Ana Espinosa, Elisabeth Thiering, Mustafa Atalay, Niina Pitkänen, Ioanna Ntalla, Anna E Jonsson, Rachel M. Freathy, Ville Karhunen, Carla M.T. Tiesler, Catherine Allard, Andrew Crawford, Susan M. Ring, Mads Melbye, Per Magnus, Fernando Rivadeneira, Line Skotte, Torben Hansen, Julie Marsh, Mònica Guxens, John Holloway, Harald Grallert, Vincent W.V. Jaddoe, William L Lowe, Theano Roumeliotaki, Andrew T. Hattersley, Virpi Lindi, Katja Pahkala, Kalliope Panoutsopoulou, Marie Standl, Claudia Flexeder, Luigi Bouchard, Ellen Aagaard Nohr, Loreto Santa Marina, Manolis Kogevinas, Harri Niinikoski, George Dedoussis, Joachim Heinrich, Rebecca M. Reynolds, Timo A. Lakka, Eleftheria Zeggini, Olli T. Raitakari, Leda Chatzi, Hazel Inskip, Mariona Bustamante, Marie-France Hivert, Marjo-Riitta Jarvelin, Thorkild I.A. Sørensen, Craig Pennell, Janine F. Felix, Bo Jacobsson, Frank Geller, David M. Evans & Debbie A. Lawlor, 2018, International Journal of Obesity, 42(4), 775-784
DOI: 10.1038/ijo.2017.248
Type: article
Eating in the absence of hunger
Anna Fogel, Keri McCrickerd, Lisa Fries, Ai Ting Goh, Phaik Ling Quah, Mei Jun Chan, Jia Ying Toh, Yap-Seng Chong, Kok Hian Tan, Fabian Yap, Lynette P. Shek, Michael J. Meaney, Birit F.P. Broekman, Yung Sueng Lee, Keith M. Godfrey, Mary F.F. Chong & Ciaran G. Forde, 2018, Physiology & Behavior
DOI: 10.1016/j.physbeh.2018.03.033
Type: article