Staff

Lead researchers

Professor Ian Sinclair

Professor of Engineering Materials
Connect with Ian

Email: I.Sinclair@soton.ac.uk

Other researchers

Professor Simon Coles

Professor of Structural Chemistry

Research interests

  • The work we do is highly collaborative and multidisciplinary and can broadly be split into three overlapping themes:
  • 1) National Crystallography Service (NCS, www.ncs.ac.uk) & Physical Sciences Data-science Service (PSDS, www.psds.ac.uk) These national centres provide centralised facilities for UK researchers at a level that is beyond that achievable in any single institution. The NCS provides data collection and crystal structure analysis for the UK chemistry community. It also performs projects based on more advanced techniques, involving a dedicated team of experts employing cutting edge techniques and the use of very high-powered laboratory diffractometers or the UK synchrotron, Diamond. The PSDS provides national-level access to databases and is building infrastructure on top of these to drive and support data-driven approaches to scientific discovery.
  • 2) Structural Chemistry We have an interest in determining the mechanisms of solid-state reactions and transformations and use a variety of diffraction and physical characterisation methods for this. Other work focuses on discovering and investigating structure-property relationships, the determination of charge densities and their properties and 'value-added' quantum mechanical calculations to compute properties from crystal structures. We also collaborate with other disciplines in a number of areas such as macromolecular crystallography (Biology), crystal growth (biology) and CT imaging (Engineering).
Connect with Simon

Email: S.J.Coles@soton.ac.uk

Professor Mark Spearing

Vice-President (Research & Enterprise)
Connect with Mark

Email: S.M.Spearing@soton.ac.uk

Emeritus Professor Chris Clayton

Connect with Chris

Email: C.Clayton@soton.ac.uk

Professor Jeremy Frey

Professor of Physical Chemistry
Connect with Jeremy

Email: J.G.Frey@soton.ac.uk

Emeritus Professor Mark Nixon

Research interests

  • My research interests are in image processing and computer vision.
  • I have helped to develop new techniques for static and moving shape extraction (both parametric and non-parametric) which have found application in automatic face and automatic gait recognition and in medical image analysis.
Connect with Mark

Email: msn@ecs.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Small airways disease in mild and moderate chronic obstructive pulmonary disease
Hyun-Kyoung Koo, Dragos M. Vasilescu, Steven Booth, Aileen Hsieh, Orestis L. Katsamenis, Nick Fishbane, W. Mark Elliott, Miranda Kirby, Peter Lackie, Ian Sinclair, Jane A. Warner, Joel D. Cooper, Harvey O. Coxson, Peter D. Pare, James C. Hogg & Tillie-Louise Hackett, 2018, The Lancet Respiratory Medicine, 6(8), 591-602
DOI: 10.1016/S2213-2600(18)30196-6
Type: article
A 3D printed bilayer oral solid dosage form combining metformin for prolonged and glimepiride for immediate drug delivery
Christos I. Gioumouxouzis, Apostolos Baklavaridis, Orestis L. Katsamenis, Catherine K. Markopoulou, Nikolaos Bouropoulos, Dimitrios Tzetzis & Dimitrios G. Fatouros, 2018, European Journal of Pharmaceutical Sciences, 120, 40-52
DOI: 10.1016/j.ejps.2018.04.020
Type: article
Calibration of robotic manipulator systems for cone beam tomography imaging
Thomas Blumensath, Neil O'Brien & Charles Wood, 2018, IEEE Transactions on Nuclear Science, 65(7), 1384-1393
DOI: 10.1109/TNS.2018.2843807
Type: article
Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age
Juan, Antonio Nunez, Alice Goring, Behzad Javaheri, H. Razi, Diego Gomez-Nicola, E. Hesse, A.A. Pitsillides, Philipp Thurner, Philipp Schneider & Claire Clarkin, 2018, European Cells & Materials, 35, 281-299
DOI: 10.22203/eCM.v035a20
Type: article
Image-enhanced modelling of residual compressive after impact strength in laminated composites
Daniel Bull, Simon Spearing & Ian Sinclair, 2018, Composite Structures, 192, 20-27
DOI: 10.1016/j.compstruct.2018.02.047
Type: article