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Research project

Dr Vince O'Connor MRC TSE Highlight

Staff

Lead researchers

Professor Vincent O'connor

Professor of Neurochemistry

Research interests

  • Molecular mechanism of synaptic function and dysfunction
  • Synaptic degeneration
  • Genetic models of synaptic and neuronal dysfunction
Connect with Vincent

Email: V.M.OConnor@soton.ac.uk

Other researchers

Emeritus Professor Hugh Perry MA, DPhil, FMedSci

Connect with Hugh

Email: V.H.Perry@soton.ac.uk

Research outputs

Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice
Zuzana Sisková, Nik K Sanyal, Adam Orban, Vincent O'Connor & V Hugh Perry, 2010, Biochemical Society Transactions, 38(2), 471-475
DOI: 10.1042/BST0380471
Type: article
Synaptopathy: dysfunction of synaptic function?
Nils Brose, Vincent O'Connor & Paul Skehel, 2010, Biochemical Society Transactions, 38(2), 443-444
DOI: 10.1042/BST0380443
Type: article
Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease
A.A. Asuni, K. Hilton, Z. Siskova, K. Lunnon, R. Reynolds, V.H. Perry & V. O'Connor, 2010, Neuroscience, 165(3), 662-674
DOI: 10.1016/j.neuroscience.2009.10.047
Type: article
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
B.C. Gray, Z. Siskova, V.H. Perry & V. O'Connor, 2009, Neurobiology of Disease, 35(1), 63-74
DOI: 10.1016/j.nbd.2009.04.001
Type: article
Degenerating synaptic boutons in prion disease. Microglia activation without synaptic stripping
Zuzana Siskova, Anton Page, Vincent O'Connor & Victor Hugh Perry, 2009, The American Journal of Pathology, 175(4), 1610-1621
DOI: 10.2353/ajpath.2009.090372
Type: article