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Research project

Core Capability for Chemistry Research in Southampton - Brown - EPSRC

Staff

Lead researcher

Professor Richard Brown

Professor of Organic Chemistry

Research interests

  • Organic synthesis
  • Total synthesis of natural products
  • Asymmetric synthesis
Connect with Richard

Email: R.C.Brown@soton.ac.uk

Other researchers

Professor Gill Reid

PROFESSOR OF CHEMISTRY

Research interests

  • Synthetic inorganic chemistry
  • Design and synthesis of new macrocyclic and multidentate ligands involving donor atoms from Groups 15 (P, As, Sb, Bi) and 16 (S, Se, Te)
  • Coordination chemistry with s-, p-, d- and f-block metal ions
Connect with Gill

Email: G.Reid@soton.ac.uk

Research outputs

Spatio-temporal detachment of homogeneous electron transfer in controlling selectivity in mediated organic electrosynthesis
Jack W. Hodgson, Ana A. Folgueiras Amador, Derek Pletcher, David C. Harrowven, Guy Denuault & Richard C.D. Brown, 2023, Faraday Discussions, 247, 302-323
DOI: 10.1039/D3FD00089C
Type: article
Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C
Joseph Richard Stephenson Clarke, Leon R Douglas, Patrick Duriez, Dimitrios-Ilias Balourdas, Andreas C. Joerger, Raniya Khadiullina, Emil Bulatov & Matthias G.J. Baud, 2022, ACS Pharmacology and Translational Science, 5(11), 1169–1180
DOI: 10.1021/acsptsci.2c00164
Type: article
Cathodic radical cyclisation of aryl halides using a strongly-reducing catalytic mediator in flow
Ana Folgueiras Amador, Alexander Teuten, Mateo Salam Perez, James Pearce, Guy Denuault, Derek Pletcher, Phillip James Parsons, David C. Harrowven & Richard C.D. Brown, 2022, Angewandte Chemie International Edition, 61(35)
DOI: 10.1002/anie.202203694
Type: article
Biophysical survey of small-molecule β-catenin inhibitors
Michael, Arron McCoy, Dominique Spicer, Neil J. Wells, Kurt Hoogewijs, Marc Fiedler & Matthias G.J. Baud, 2022, Journal of Medicinal Chemistry, 65(10), 7246–7261
DOI: 10.1021/acs.jmedchem.2c00228
Type: article
Relating Conformational Equilibria to Conformer-Specific Lipophilicities: New Opportunities in Drug Discovery
2022, Angewandte Chemie, 61(7)
DOI: 10.1002/anie.202114862
Type: article