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Research project

Core Capability for Chemistry Research in Southampton - Brown - EPSRC

Staff

Lead researchers

Professor Richard Brown

Professor of Organic Chemistry

Research interests

  • Organic synthesis
  • Total synthesis of natural products
  • Asymmetric synthesis
Connect with Richard

Email: R.C.Brown@soton.ac.uk

Other researchers

Professor Gill Reid

PROFESSOR OF CHEMISTRY

Research interests

  • Synthetic inorganic chemistry
  • Design and synthesis of new macrocyclic and multidentate ligands involving donor atoms from Groups 15 (P, As, Sb, Bi) and 16 (S, Se, Te)
  • Coordination chemistry with s-, p-, d- and f-block metal ions
Connect with Gill

Email: G.Reid@soton.ac.uk

Research outputs

De Novo enantioselective synthesis of hexafluorinated d-glucose
Sébastien Depienne, Clement Q Fontenelle, Mark Light, Kristof Van Hecke & Bruno Linclau, 2024, Journal of Organic Chemistry, 89(19), 14291-14304
DOI: 10.1021/acs.joc.4c01724
Type: article
Exploring 2-sulfonylpyrimidine warheads as acrylamide surrogates for targeted covalent inhibition: a BTK story
Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, Jonathan C. Strefford, Graham Packham & Matthias G.J. Baud, 2024, Journal of Medicinal Chemistry, 67(16), 13572-13593
DOI: 10.1021/acs.jmedchem.3c01927
Type: article
Conformational analysis of 1,3-difluorinated alkanes
William G. Poole, Florent Peron, Stephen J. Fox, Neil Wells, Chris Kriton Skylaris, Jonathan W. Essex, Ilya Kuprov & Bruno Linclau, 2024, Journal of Organic Chemistry, 89(12), 8789–8803
DOI: 10.1021/acs.joc.4c00670
Type: article
Quantitative analysis of 2D EXSY NMR spectra of strongly coupled spin systems in transmembrane exchange
Dmitry Shishmarev, Clement Q. Fontenelle, Bruno Linclau, Ilya Kuprov & Philip W. Kuchel, 2023, ChemBioChem, e202300597
DOI: 10.1002/cbic.202300597
Type: article
Rapid investigation of the effect of binary and ternary solvent gradient mixtures on reaction outcomes using a continuous flow system
Dawid Drelinkiewicz, Tom J.A. Corrie & Richard J. Whitby, 2023, Reaction Chemistry and Engineering
DOI: 10.1039/d3re00464c
Type: article