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Research project

Clough PG/12/18/29453 Maternal over-nutrition and offspring microvascular function

Staff

Lead researcher

Emeritus Professor Geraldine Clough

Research interests

  • Early identification of risk of small vessel dysfunction in cardio-metabolic disease
  • Mechanisms underlying the developmental priming of vascular plasticity and endothelial dysfunction by maternal diet
  • Development of novel devices and approaches for the multiscale assessment of the dynamics of microvascular perfusion
Connect with Geraldine

Email: G.F.Clough@soton.ac.uk

Other researchers

Professor Chris Byrne

Professor of Endocrinol & Met
Connect with Chris

Email: C.D.Byrne@soton.ac.uk

Research outputs

An image-based computation of microvascular dysfunction
2017
Type: thesis
Developmental conditioning of endothelium-derived hyperpolarizing factor-mediated vasorelaxation
Rebecca Stead, Moji G Musa, Claire L Bryant, Stuart A Lanham, David A Johnston, Richard Reynolds, Christopher Torrens, Paul A Fraser & Geraldine F Clough, 2016, Journal of Hypertension, 34(3), 452-63; discussion 463
DOI: 10.1097/HJH.0000000000000833
Type: article
Developmental conditioning of the vasculature
G. Clough, 2015, Comprehensive Physiology, 5, 397-438
DOI: 10.1002/cphy.c140037
Type: article
The microvasculative: a target for nutritional programming and later risk of cardio-metabolic disease
M.G. Musa, C. Torrens & G. Clough, 2013, Acta Physiologica, 210(1), 31-45
DOI: 10.1111/apha.12131
Type: article
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice
Christopher Torrens, P. Ethirajan, K.D. Bruce, F.R. Cagampang, R.C. Siow, Mark A. Hanson, Christopher D. Byrne, G.E. Mann & G.F. Clough, 2012, PLoS ONE, 7(12), e0050671
DOI: 10.1371/journal.pone.0050671
Type: article