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Research project

C Cooper 17702 (MAVIDOS)

Staff

Lead researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Other researchers

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Elaine Dennison

Personal Chair

Research interests

  • The epidemiology of musculoskeletal disease, particularly those conditions common in later life (osteoporosis and osteoarthritis)
Connect with Elaine

Email: emd@mrc.soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Research outputs

Hypertension development by midlife and the roles of pre-morbid cognitive function, sex, and their interaction
Drew M. Altschul, Christina Wraw, Geoff Der, Catharine Gale & Ian J. Deary, 2019, Hypertension, 73(4), 812-819
DOI: 10.1161/HYPERTENSIONAHA.118.12164
Type: article
FUT2 Genetic Variants and reported respiratory and gastrointestinal illnesses during infancy
Sheila Barton, Robert Murray, Karen Lillycrop, Hazel Inskip, Nicholas Harvey, Cyrus Cooper, Neerja Karnani, Irma Silva Zolezzi, Norbert Sprenger, Keith Godfrey & Aristea Binia, 2019, The Journal of Infectious Diseases, 219(5), 836–843
DOI: 10.1093/infdis/jiy582
Type: article
Factory and construction work is associated with an increased risk of severe lumbar spinal stenosis on MRI: A case control analysis within the wakayama spine study
Yuyu Ishimoto, Cyrus Cooper, Georgia Ntani, Hiroshi Yamada, Hiroshi Hashizume, Kazuhiro Nagata, Shigeyuki Muraki, Sakae Tanaka, Noriko Yoshimura, Munehito Yoshida & Karen Walker-Bone, 2019, American Journal of Industrial Medicine
DOI: 10.1002/ajim.22957
Type: article
An atlas of genetic influences on osteoporosis in humans and mice
John A. Morris, John P Kemp, Scott E. Youlten, Laetitia Laurent, John G. Logan, Ryan Chai, Nicholas A Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu Mohanty, C Marcelo Sergio, Julian Quinn, Loan Nguyen-Yamamoto, Aimee Lee Luco, Jinchu Vijay, Marie-Michelle Simon, Albena Pramatarova, Carolina Medina-Gomez, Katerina Trajanoska, Elena J. Ghirardello, Natalie C. Butterfield, Katharine F. Curry, Victoria D. Leitch, Penny C. Sparkes, Anne-Tounsia Adoum, Naila S. Mannan, Davide Komla-Ebri, Andrea S. Pollard, Hannah F. Dewhurst, Thomas Hassell, Michael-John G. Beltajar, Douglas J. Adams, Suzanne M. Vaillancourt, Stephen K. Kaptoge, Paul Baldock, Cyrus Cooper, Jonathan Reeve, Evangelia Ntzani, Evangelos Evangelou, Claes Ohlsson, David Karasik, Fernando Rivadeneira, Douglas R. Kiel, Jonathan H. Tobias, Celia L. Gregson, Nicholas Harvey, Elin Grundberg, David Goltzman, David J Adams, Christopher J. Lelliott, David A. Hinds, Cheryl L. Ackert-Bicknell, Yi-Hsiang Hsu, Matthew T. Maurano, Peter I. Croucher, Graham R. Williams, J.H. Duncan Bassett, David M. Evans & J. Brent Richards, 2019, Nature Genetics, 51(2), 258-266
DOI: 10.1038/s41588-018-0302-x
Type: article
Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation
Elizabeth Curtis, Nevena Krstic, Eloise Cook, Stefania D'angelo, Sarah Crozier, Rebecca Moon, Robert Murray, Emma Garratt, Paula Costello, Jane Cleal, Brogan Ashley, Nicholas Bishop, Stephen Kennedy, Aris T. Papageorghiou, Inez Schoenmakers, Robert Fraser, Saurabh V. Gandhi, Ann Prentice, M. Kassim Javaid, Hazel Inskip, Keith Godfrey, Christopher Bell, Karen Lillycrop, Cyrus Cooper & Nicholas Harvey, 2019, Journal of Bone and Mineral Research, 34(2), 231-240
DOI: 10.1002/jbmr.3603
Type: article