Interdisciplinary Dementia and Ageing Centre

Publications

Browse our published work and read our findings.

Systemic exposure to lipopolysaccharide from Porphyromonas gingivalis induces bone loss-correlated Alzheimer’s disease-like pathologies in middle-aged mice

Yebo Gu, Zhou Wu, Fan Zeng, Muzhou Jiang, Jessica L. Teeling, Junjun Ni & Ichiro Takahashi, 2020, Journal of Alzheimer's Disease, 78(1), 61-74

DOI: 10.3233/JAD-200689

Type: article

Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

Matthew MacGregor Sharp, Satoshi Saito, Abby Keable, Maureen Gatherer, Roxana Aldea, Nivedita Agarwal, Julie E. Simpson, Stephen B. Wharton, Roy O. Weller & Roxana O. Carare, 2020, Acta Neuropathologica Communications, 8(1)

DOI: 10.1186/s40478-020-01009-1

Type: article

Neurofilaments: neurobiological foundations for biomarker applications

Arie R. Gafson, Nicolas R. Barthélemy, Pascale Bomont, Roxana-Octavia Carare, Heather D. Durham, Jean-Pierre Julien, Jens Kuhle, David Leppert, Ralph A. Nixon, Roy O. Weller, Henrik Zetterberg & Paul M. Matthews, 2020, Brain, 143(7), 1975–1998

DOI: 10.1093/brain/awaa098

Type: article

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment

Aisling McFall, Tuuli M Hietamies, Ashton Bernard, Margaux Aimable, Stuart M Allan, Philip M Bath, Gaia Brezzo, Roxana O Carare, Hilary V Carswell, Andrew N Clarkson, Gillian Currie, Tracy D Farr, Jill H Fowler, Mark Good, Atticus H Hainsworth, Catherine Hall, Karen Horsburgh, Rajesh Kalaria, Patrick Kehoe, Catherine Lawrence, Malcolm Macleod, Barry W McColl, Alison McNeilly, Alyson A Miller, Scott Miners, Vincent Mok, Michael O'Sullivan, Bettina Platt, Emily S Sena, Matthew Sharp, Patrick Strangward, Stefan Szymkowiak, Rhian M Touyz, Rebecca C Trueman, Claire White, Chris McCabe, Lorraine M Work & Terence J Quinn, 2020, Journal of Cerebral Blood Flow & Metabolism, 40(7), 1402-1414

DOI: 10.1177/0271678X20910552

Type: article

ApoE4 astrocytes secrete basement membranes rich in fibronectin and poor in laminin compared to ApoE3 astrocytes

Abby Keable, Ronan O'Neill, Matthew MacGregor Sharp, Maureen Gatherer, Ho Ming Yuen, David Annandale Johnston, Roy Oliver Weller & Roxana Octavia Carare, 2020, International Journal of Molecular Sciences, 21(12), 1-13

DOI: 10.3390/ijms21124371

Type: article