Education

Developing nucleic acid therapeutics to restore sight-loss associated with albinism

• PhD student: Laurie Hughes
• Academic supervisors: Dr Ysobel Baker, Dr James Self, Professor Eugen Stulz

OPTIMISE: towards personalised care strategies for patients with cochlear implants via customised pathway modelling and prediction

• PhD student: Bhagyashree Sirohi
• Academic supervisors: Professor Tracey Newman, Dr Edilson Arruda

Determinants of skeletal development, bone loss and fracture risk: an investigation using a novel computer vision assessment of bone microarchitecture

• PhD student: Thomas Cox
• Academic supervisors: Professor Nicholas Harvey, Professor Kate Ward, Dr Sasan Mahmoodi

A multidisciplinary study into air pollution-associated transition metal homeostasis in the alveoli

• PhD student: Liam Edgeway
• Academic supervisors: Dr Matt Loxham, Professor Gavin Foster, Professor Mark Jones, Professor J Andy Milton

Investigating the regulatory role of central carbon metabolism on cell fate decisions during liver development and regeneration

• PhD student: Joshua Green Jenkinson
• Academic supervisors: Dr Nicole Prior, Professor Jonathan Swann

Understanding how lysosomes become dysfunctional in neurodegeneration

• PhD student: Charlie Ellis
• Academic supervisors: Dr Arjuna Ratnayaka, Dr David Tumbarello, Professor Louise Serpell (University of Sussex)

Developing organoids to model liver zonation in vitro

• PhD student: Amanda Gilbert
• Academic supervisors: Dr Nicole Prior, Dr Jonathan West

Gut bacteria and the brain: the surprising impact of bacteriophages

• PhD student: Daniela Rothschild Rodriguez
• Academic supervisors: Dr Franklin Luzia de Nobrega, Professor Jessica Teeling, Professor Jerome Swinny (University of Portsmouth)

Analysing the functional significance of a primate-specific non-canonical glutamate receptor

• PhD student: Steven Houghton
• Academic supervisors: Dr Mariana Vargas-Caballero, Professor Katrin Deinhardt

Yomna Moqidem, Defining the role of Factor Inhibiting HIF (FIH) as a key regulator of extracellular matrix homeostasis

• Academic supervisors: Dr Yihua Wang, Prof Mark Jones and Dr Andrea Bucci (University of Portsmouth).

Boronate PVA conjugates and hydrogels to improve chemotherapy for the treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

• PhD student: Anne Aarvik
• Academic supervisors: Dr George Williams, Dr Nicole Prior, Professor Nick Evans

Extending the chemical space of mAb based cancer treatment with DNA nanostructures

• PhD student: Alexandros Angelopoulos
• Academic supervisors: Professor Eugen Stulz, Professor Sean Lim

THERMOHUMAN: Understanding human thermal behaviour and sensitivity to build health and resilience to climate change

• PhD student: Aislin Fields
• Academic supervisors: Dr Davide Filingeri, Professor Joanne Turney, Dr Adrian Lai

Drug-microbiome-host interactions in Parkinson’s disease

• PhD student: Linda Guantai
• Academic supervisors: Dr Fatima Pereira, Professor Jerome Swinny (University of Portsmouth), Dr Franklin Nobrega

Phage mitigation of Klebsiella infection: a new approach for AMR

• PhD student: Rachel Buchanan
• Academic supervisors: Dr Franklin Nobrega, Professor Vincent O'Connor

‘Big Data’ in inflammatory bowel disease; personalising care through genomics, prediction, and clinical data integration

• PhD student: Fernando Vasquez Lopez
• Academic supervisors: Dr James Ashton, Dr Jagmohan Chauhan, Professor Sarah Ennis, Dr Guo Cheng

Understanding T cell exhaustion in the context of immunotherapy

• PhD student: Disha Mehta
• Academic supervisors: Dr Owen Rackham, Professor Sean Hua Lim

Machine learning to improve multidisciplinary decision-making in the assessment and management of oesophageal adenocarcinoma

• PhD student: Navamayooran Thavanesan
• Academic supervisors: Professor Tim Underwood, Professor Age Chapman, Dr Ganesh Vigneswaran

Next-generation data-driven approaches for predicting disease states in cells and tissues

• PhD student: Moi Nicholas
• Academic supervisors: Dr Owen Rackham, Professor Paul Skipp

Machine learning of clinical outcomes from time-series and imaging data

• PhD student: Alexander Thomas
• Academic supervisors: Professor Ben MacArthur, Professor Mahesan Niranjan, Dr Julian Legg (UHS NHS FT)

Computational modelling to understand the key determinants of placental IgG transfer

• PhD student: Lois Brewer
• Academic supervisors: Dr Bram Sengers, Dr Chrissie Jones, Professor Rohan Lewis

Ultrasonic microbubbles as an advanced therapy for drug delivery in bone repair

• PhD student: Sam Sloan
• Academic supervisors: Professor Nicholas Evans, Dr Janos Kanczler