About
Patrick joined the Cancer Sciences School in 2006 to create a Protein Facility. As of 2024, he has 30 years of experience in molecular biology and 20 years of experience in protein expression and protein purification.
The Protein Facility has produced over 100 different proteins and Patrick has contributed to over 45 publications.
Research
Research groups
Member of:
Research interests
- Cancer immunotherapy
- Production of recombinant proteins
Current research
The Protein Facility is focused on the production of recombinant proteins involved in cancer. The process involves all the steps from cloning and expression to purification and quality control.
The Protein Facility has strong interactions with structure biologists in the Institute of Life Sciences.
Publications
38 publications
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Charles N. Birts, Sharandip K. Nijjar, Charlotte A. Mardle, Franciane Hoakwie, Patrick J. Duriez, Jeremy P. Blaydes & Ali Tavassoli,
2013, Chemical Science, 4(8), 3046-3057
DOI: 10.1039/c3sc50481f
Type: article
Hanae Benelkebir, Christopher Hodgkinson, Patrick J. Duriez, Annette L. Hayden, Rosemary A. Bulleid, Simon J. Crabb, Graham Packham & A. Ganesan,
2011, Bioorganic & Medicinal Chemistry
Type: article
Alexander U. Lüthi, Sean P. Cullen, Edel A. McNeela, Patrick J. Duriez, Inna S. Afonina, Clare Sheridan, Gabriela Brumatti, Rebecca C. Taylor, Kristof Kersse, Peter Vandenabeele, Ed C. Lavelle & Seamus J. Martin,
2009, Immunity, 31(1), 84-98
Type: article
Emma M. Creagh, Gabriela Brumatti, Clare Sheridan, Patrick J. Duriez, Rebecca C. Taylor, Sean P. Cullen, Colin Adrain & Seamus J. Martin,
2009, PLoS ONE, 4(3), e5055
Type: article
Sean P. Cullen, Colin Adrain, Alexander U. Lüthi, Patrick J. Duriez & Seamus J. Martin,
2007, PLoS ONE, 176(4), 435-44
Type: article
Colin Adrain, Patrick J. Duriez, Gabriela Brumatti, Petrina Delivani & Seamus J. Martin,
2006, The Journal of Biological Chemistry, 281(12), 8118-8125
Type: article
Petrina Delivani, Colin Adrain, Rebecca C. Taylor, Patrick J. Duriez & Seamus J. Martin,
2006, Molecular Cell, 21(6), 761-773
Type: article
Michelle M. Hill, Colin Adrain, Patrick J. Duriez, Emma M. Creagh & Seamus J. Martin,
2004, The EMBO Journal, 23(10), 2134-45
Type: article
Farrell MacKenzie, Patrick Duriez, Fred Wong, Michela Noseda & Aly Karsan,
2004, The Journal of Biological Chemistry, 279(12), 11657-11663
Type: article
Christopher Hull, Graeme McLean, Fred Wong, Patrick J. Duriez & Aly Karsan,
2002, Journal of Immunology, 169(5), 2611-2618
Type: article