About
Patrick joined the Cancer Sciences School in 2006 to create a Protein Facility. As of 2024, he has 30 years of experience in molecular biology and 20 years of experience in protein expression and protein purification.
The Protein Facility has produced over 100 different proteins and Patrick has contributed to over 45 publications.
Research
Research groups
Member of:
Research interests
- Cancer immunotherapy
- Production of recombinant proteins
Current research
The Protein Facility is focused on the production of recombinant proteins involved in cancer. The process involves all the steps from cloning and expression to purification and quality control.
The Protein Facility has strong interactions with structure biologists in the Institute of Life Sciences.
Publications
38 publications
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Edwin Garcia, Annette Hayden, Charles Birts, Edward Britton, Connor Rogerson, Christopher W. Bleaney, Andrew Cowie, Karen Pickard, Massimiliano Mellone, Clarisa Choh, Mathieu Derouet, Patrick Duriez, Fergus Noble, Michael J. White, John N. Primrose, Jonathan C. Strefford, Matthew Rose-Zerilli, Gareth J. Thomas, Yeng Ang, Andrew D. Sharrocks, Rebecca C. Fitzgerald, Timothy J. Underwood, Shona MacRae, Nicola Grehan, Zarah Abdullahi, Rachel de la Rue, Ayesha Noorani, Rachael Fels Elliott, Nadeera de Silva, Jan Bornschein, Maria O’Donovan, Gianmarco Contino, Tsun Po Yang, Hamza Chettouh, Jason Crawte, Barbara Nutzinger, Paul A.W. Edwards, Laura Smith, Ahmad Miremadi, Shalini Malhotra, Alison Cluroe, Richard Hardwick, Jim Davies, Hugo Ford, David Gilligan, Peter Safranek, Stephen J. Hayes, Andrew Davies, John Saunders & Michael Scott,
2019, Scientific Reports, 9(1), 1-5
Type: letterEditorial
Sergio Regufe da Mota, Sarah Bailey, Rosemary A. Strivens, Annette L. Hayden, Leon R. Douglas, Patrick J. Duriez, M. Teresa Borrello, Hanae Benelkebir, A. Ganesan, Graham Packham & Simon J. Crabb,
2018, Cancer Cell International, 18(71), 1-9
Type: article
Xiaojie Yu, Hak Chan, Christian Orr, Osman Dadas, Steven Booth, Lekh Dahal, Christine Penfold, Lyn O'Brien, Christopher Mockridge, Ruth French, Patrick Duriez, Leon Douglas, Arwen R. Pearson, Mark Cragg, Ivo Tews, Martin Glennie & Ann L. White,
2018, Cancer Cell, 33(4), 664-675
Type: article
Alexandra J. Allen, Chuan Wang, Lisa J. Caproni, Gessa Sugiyarto, Elena L. Harden, Leon R. Douglas, Patrick J. Duriez, Kinga Karbowniczek, Jon Extance, Paul J. Rothwell, Ifeayinwa Orefo, John P. Tite, Freda K. Stevenson, Christian H. Ottensmeier & Natalia Savelyeva,
2018, Cancer Immunology Immunotherapy, 1-12
Type: article
Lekh N Dahal, Lang Dou, Khiyam Hussain, Rena Liu, Alexander Earley, Kerry L Cox, Salome Murinello, Ian Tracy, Francesco Forconi, Andrew J Steele, Patrick Duriez, Diego Gomez-Nicola, Jessica L Teeling, Martin J Glennie, Mark S Cragg & Stephen A Beers,
2017, Cancer Research, 77(13), 3619-3631
Type: article
Maria Teresa Borrello, Benjamin Schinor, Katharina Bartels, Hanae Benelkebir, Sara Pereira, Wafa T. Al-Jamal, Leon Douglas, Patrick J. Duriez, Graham Packham, Günter Haufe & Anusha Ganesan,
2017, Bioorganic & Medicinal Chemistry Letters, 27(10), 2099-2101
Type: article
Edwin Garcia, Annette Hayden, Charles Birts, Edward Britton, Andrew Cowie, Karen Pickard, Massimiliano Mellone, Clarisa Choh, Mathieu Derouet, Patrick Duriez, Fergus Noble, Michael J. White, John Primrose, Jonathan C. Strefford, Matthew Rose-Zerilli, Gareth Thomas, Yeng Ang, Andrew D. Sharrocks, Rebecca C. Fitzgerald & Timothy J. Underwood,
2016, Scientific Reports, 6(32417), 1-12
DOI: 10.1038/srep32417
Type: article
Clemens Hermann, Andy Van Hateren, Nico Trautwein, Andreas Neerincx, Patrick J. Duriez, Stefan Stevanović, John Trowsdale, Janet E. Deane, Tim Elliott & Louise H. Boyle,
2016, eLife, 4, 1-22
Type: article
Joseph F Collin, James W Wells, Barbara Czepulkowski, Linden Lyne, Patrick J Duriez, Alison H Banham, Ghulam J Mufti & Barbara-Ann Guinn,
2015, Genes, Chromosomes and Cancer, 54(5), 288-302
DOI: 10.1002/gcc.22242
Type: article
Thomas R.W. Tipton, Ali Roghanian, Robert J. Oldham, Matthew J. Carter, Kerry L. Cox, C. Ian Mockridge, Ruth R. French, Lekh N. Dahal, Patrick J. Duriez, Philip G. Hargreaves, Mark S. Cragg & Stephen A. Beers,
2015, Blood, 125(12), 1901-1909
Type: article