Publications

Explore our research outputs and impact in-depth.

Pan-cancer deconvolution of tumour composition using DNA methylation

Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J Thomas, Andrew Feber & Tim Fenton, 2018, Nature Communications, 9

DOI: 10.1038/s41467-018-05570-1

Type: article

PD-1 blockade and CD27 stimulation activate distinct transcriptional programs that synergize for CD8+ T-cell driven anti-tumor immunity

Sarah Buchan, Mohannad Fallatah, Stephen Thirdborough, Vadim Y. Taraban, Anne Rogel, Lawrence J. Thomas, Christine Penfold, Li-Zhen He, Michael Curran, Tibor Keler & Aymen Al-Shamkhani, 2018, Clinical Cancer Research, 24(10), 2383-2394

DOI: 10.1158/1078-0432.CCR-17-3057

Type: article

CONFIRM

Dean A. Fennell, Emma Kirkpatrick, Kelly Cozens, Mavis Nye, Jason Lester, Gerard Hanna, Nicola Steele, Peter Szlosarek, Sarah Danson, Joanne Lord, Christian Ottensmeier, Daniel Barnes, Stephanie Hill, Michail Kalevras, Thomas Maishman & Gareth Griffiths, 2018, Trials, 19(233), 1-10

DOI: 10.1186/s13063-018-2602-y

Type: article

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Mohammed M. Naiyer, Sorcha A. Cassidy, Andrea Magri, Vanessa Cowton, Kevin Chen, Salah Mansour, Hariklia Kranidioti, Berenice Mbiribindi , Pauline Rettman, Scott Harris, Liam J. Fanning, Arend Mulder, Franz H.J. Claas, Andrew D. Davidson, Arvind H. Patel, Marco A. Purbhoo & Salim I. Khakoo, 2017, Science immunology, 2(15)

DOI: 10.1126/sciimmunol.aal5296

Type: article

Upregulated glucose metabolism correlates inversely with CD8+ T-cell infiltration and survival in squamous cell carcinoma

Christian H. Ottensmeier, Kate L. Perry, Elena L. Harden, Jana Stasakova, Veronika Jenei, Jason Fleming, Oliver Wood, Jeogmin Woo, Christopher H. Woelk, Gareth J. Thomas & Stephen M. Thirdborough, 2016, Cancer Research, 76(14), 4136-4148

DOI: 10.1158/0008-5472.CAN-15-3121

Type: article