Research project

The role of nuclear phosphoinositides in epigenetic signalling - N Divecha - BBSRC

Lead researchers:

Professor Nullin Divecha
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Lead researchers

Professor Nullin Divecha

Professor of Cellular Signalling

Connect with Nullin

Email: N.Divecha@soton.ac.uk

Research outputs

Mechanisms of SARS-CoV-2 inactivation using UVC laser radiation

George Devitt, Peter B. Johnson, Niall Hanrahan, Simon I.R. Lane, Magdalena C. Vidale, Bhavwanti Sheth, Joel D. Allen, Maria V. Humbert, Cosma M. Spalluto, Rodolphe C. Herve, Karl Staples, Jonathan J. West, Robert Forster, Nullin Divecha, Chris McCormick, Max Crispin, Nils Hempler, Graeme P.A. Malcolm & Sumeet Mahajan, 2024, ACS Photonics, 11(1), 42-52

DOI: 10.1021/acsphotonics.3c00828

Type: article

PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1

A. Poli, F.A. Pennacchio, A. Ghisleni, M. di Gennaro, M. Lecacheur, P. Nastaly, M. Crestani, F.M. Pramotton, F. Iannelli, G. Beznusenko, A. A Mironov, V. Panzetta, S. Fusco, B. Sheth, D. Poulikakos, A. Ferrari, N. Gauthier, P.A. Netti, N. Divecha & P. Maiuri, 2023, Nature Communications, 14(1)

DOI: 10.1038/s41467-023-37064-0

Type: article

Identification and optimization of a novel series of selective PIP5K inhibitors

D.M. Andrews, S. Cartic, S. Cosulich, N. Divecha, P. Faulder, V. Flemington, O. Kern, J.G. Kettle, E. MacDonald, J. McKelvie, K.G. Pike, B. Roberts, R. Rowlinson, J.M. Agnos, M. Stockley, M.E. Swarbrick, I. Treinies & M.J. Waring, 2021, Bioorganic & Medicinal Chemistry, 54

DOI: 10.1016/j.bmc.2021.116557

Type: article

Modulating phosphoinositide profiles as a roadmap for treatment in acute myeloid leukemia

S. Ratti, C. Evangelisti, S. Mongiorgi, A. De Stefano, A. Fazio, F. Bonomini, M.Y. Follo, I. Faenza, L. Manzoli, B. Sheth, M.C. Vidalle, S.T. Kimber, N. Divecha, L. Cocco & R. Fiume, 2021, Frontiers in Oncology, 11

DOI: 10.3389/fonc.2021.678824

Type: article

Exploring the controversial role of PI3K signalling in CD4+ regulatory T (T-Reg) cells

Alessandro Poli, Roberta Fiume, Sara Mongiorgi, Antonio Zaurito, Bhavwanti Sheth, Magdalena Castellano Vidalle, Shidqiyyah Abdul Hamid, Scottt. Kimber, Francesca Campagnoli, Stefano Ratti, Isabella Rusciano, Irene Faenza, Lucia Manzoli & Nullin Divecha, 2020, Advances in Biological Regulation, 76, 100722

DOI: 10.1016/j.jbior.2020.100722

Type: article