Research project

Supramolecular Designs on Dynamic Covalent Protein Recognition

Research groups:

Chemical Biology, Diagnostics and Therapeutics
Lead researcher:

Dr Sam Thompson
Research funder:

EPSRC
Status:

Not active

Staff

Lead researcher

Dr Sam Thompson

Associate Professor

Research interests

Chemical Biology
Organic Synthesis
Medicinal Chemistry

Connect with Sam

Email: Sam.Thompson@southampton.ac.uk

Collaborating research institutes, centres and groups

Chemical Biology, Diagnostics and Therapeutics

We investigate the properties of biomolecules – including an assortment of DNA, proteins, lipids and carbohydrates.

Research outputs

Single-molecule nanopore dielectrophoretic trapping of α-synuclein with lipid membranes

Jinming Wu, Tohru Yamashita, Andrew D. Hamilton, Sam Thompson & Jinghui Luo, 2023, Cell Reports Physical Science, 4(2)

DOI: 10.1016/j.xcrp.2022.101243

Type: article

Rationally designed helical peptidomimetics disrupt α-synuclein fibrillation

Clementine, Ella Bavinton, Rebecca Sternke-Hoffmann, Tohru Yamashita, Peter Knipe, Andrew D. Hamilton, Jinghui Luo & Sam Thompson, 2022, Chemical Communications, 58(33), 5132-5135

DOI: 10.1039/d2cc00212d

Type: article