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Research project

J Tod MRC The role of Eps8 in regulating pancreatic cancer G1002008

Staff

Lead researcher

Professor Gareth Thomas

Professor of Experimental Pathology

Research interests

  • Fibroblast biology and immunology
  • Tumour microenvironment
  • Cancer Immunotherapy
Connect with Gareth

Email: G.Thomas@soton.ac.uk

Research outputs

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch
Joanne Tod, Christopher Hanley, Mark R. Morgan, Marta Rucka, Toby Mellows, Maria-Antoinette Lopez, Philip Kiely, Karwan Moutasim, Steven, James Frampton, Durgagauri Sabnis, David R. Fine, Colin Johnson, John F. Marshall, Giorgio Scita, Veronika Jenei & Gareth Thomas, 2017, The Journal of Pathology, 243(1), 37-50
DOI: 10.1002/path.4923
Type: article
Suppression of hedgehog signalling promotes pro-tumourigenic integrin expression and function
Karwan A. Moutasim, Toby Mellows, Massimiliano Mellone, Marie-Antoinette Lopez, Joanne Tod, Philip C. Kiely, Karen Sapienza, Azzura Greco, Graham Neill, Shelia Violette, Paul Weinreb, John Marshall, Christian H. Ottensmeier, A.E. Sayan, V. Jenei & Gareth J. Thomas, 2014, The Journal of Pathology, 233(2), 196-208
DOI: 10.1002/path.4342
Type: article
Tumor-stromal interactions in pancreatic cancer
Jo Tod, Veronika Jenei, Gareth Thomas & David Fine, 2013, Pancreatology, 13(1), 1-7
DOI: 10.1016/j.pan.2012.11.311
Type: article