Research project

J Tod MRC The role of Eps8 in regulating pancreatic cancer G1002008

Lead researchers:

Professor Gareth Thomas
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Gareth Thomas

Professor of Experimental Pathology

Research interests

Fibroblast biology and immunology
Tumour microenvironment
Cancer Immunotherapy

Connect with Gareth

Email: G.Thomas@soton.ac.uk

Research outputs

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch

Joanne Tod, Christopher Hanley, Mark R. Morgan, Marta Rucka, Toby Mellows, Maria-Antoinette Lopez, Philip Kiely, Karwan Moutasim, Steven, James Frampton, Durgagauri Sabnis, David R. Fine, Colin Johnson, John F. Marshall, Giorgio Scita, Veronika Jenei & Gareth Thomas, 2017, The Journal of Pathology, 243(1), 37-50

DOI: 10.1002/path.4923

Type: article

Suppression of hedgehog signalling promotes pro-tumourigenic integrin expression and function

Karwan A. Moutasim, Toby Mellows, Massimiliano Mellone, Marie-Antoinette Lopez, Joanne Tod, Philip C. Kiely, Karen Sapienza, Azzura Greco, Graham Neill, Shelia Violette, Paul Weinreb, John Marshall, Christian H. Ottensmeier, A.E. Sayan, V. Jenei & Gareth J. Thomas, 2014, The Journal of Pathology, 233(2), 196-208

DOI: 10.1002/path.4342

Type: article

Tumor-stromal interactions in pancreatic cancer

Jo Tod, Veronika Jenei, Gareth Thomas & David Fine, 2013, Pancreatology, 13(1), 1-7

DOI: 10.1016/j.pan.2012.11.311

Type: article