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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise
Connect with Keith

Email: kmg@mrc.soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease
Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

FUT2 Genetic Variants and reported respiratory and gastrointestinal illnesses during infancy
Sheila Barton, Robert Murray, Karen Lillycrop, Hazel Inskip, Nicholas Harvey, Cyrus Cooper, Neerja Karnani, Irma Silva Zolezzi, Norbert Sprenger, Keith Godfrey & Aristea Binia, 2019, The Journal of Infectious Diseases, 219(5), 836–843
DOI: 10.1093/infdis/jiy582
Type: article
Maternal body mass index, gestational weight gain and the risk of overweight and obesity across childhood: an individual participant data meta-analysis
Ellis Voerman, Susana G. Santos, Bernadeta Patro Golab, Pilar Amiano, Ferran Ballester, Henrique Barros, Anna Bergström, Marie-Aline Charles, Leda Chatzi, Cecile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Graham Devereux, Merete Eggesbø, Sandra Ekström, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Keith Godfrey, Davide Gori, Veit Grote, Wojciech Hanke, Irva Hertz-Picciotto, Barbara Heude, Daniel O. Hryhorczuk, Rae-Chi Huang, Hazel Inskip, Nina Iszatt, Anne M. Karvonen, Louise C. Kenny, Berthold Koletzko, Leanne K. Küpers, Hanna Lagstrom, Irina Lehmann, Per Magnus, Renata Majewska, Johanna Makela, Yannis Manios, Fionnuala M. McAuliffe, Sheila W. McDonald, John Mehegan, Monique Mommers, Camilla S Morgen, Trevor A. Mori, George Moschonis, Deirdre Murray, Carol Ni Chaoimh, Ellen Aagaard Nohr, Anne-Marie Nybo Andersen, Emily Oken, Adriette J J M. Oostvogels, Agnieszka Pac, Eleni Papadopoulou, Juha Pekkanen, Costanza Pizzi, Kinga Polanska, Daniela Porta, Camilla Stoltenberg, Elisabeth Thiering, Lorenzo Richiardi, Sheryl L. Rifas-shiman, Luca Ronfani, Ana C. Santos, Marie Standl, Carel Thijs, Maties Torrent, Suzanne C. Tough, Tomas Trnovec, Steve Turner, Lenie van Rossem, Andrea von Berg, Martine Vrijheid, Tanja G. M. Vrijkotte, Jane West, Alet H. Wijga, John Wright, Oleksandr Zvinchuk, Thorkild I. A. Sørensen, Debbie A Lawlor, Romy Gaillard & Vincent W. V. Jaddoe, 2019, PLoS Medicine, 16(2), 1-22
DOI: 10.1371/journal.pmed.1002744
Type: article
Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life
Evelyn Loo, Elizabeth Huiwen Tham, Kee Wei Pang, Anne Goh, Oon Hoe Teoh, Yap-Seng Chong, Peter D. Gluckman, Keith Godfrey, Hugo van Bever, Bee Wah Lee, Mary Foong-Fong Chong & Lynette Pei-Chi Shek , 2019, Pediatric Allergy and Immunology, 30(1), 117-122
DOI: 10.1111/pai.12995
Type: article
Early childcare enrollment and childhood wheezing phenotypes
Elizabeth Huiwen Tham, Pei Ting Tan, Evelyn X.L. Loo, Anne Goh, Oon Hoe Teoh, Fabian Yap, Kok Hian Tan, Keith Godfrey, Hugo van Bever, Bee Wah Lee, Eric A Finkelstein, Yap-Seng Chong & Lynette Pei-Chi Shek , 2019, Pediatric Allergy and Immunology, 30(1), 122-127
DOI: 10.1111/pai.12983
Type: article
Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation
Elizabeth Curtis, Nevena Krstic, Eloise Cook, Stefania D'angelo, Sarah Crozier, Rebecca Moon, Robert Murray, Emma Garratt, Paula Costello, Jane Cleal, Brogan Ashley, Nicholas Bishop, Stephen Kennedy, Aris T. Papageorghiou, Inez Schoenmakers, Robert Fraser, Saurabh V. Gandhi, Ann Prentice, M. Kassim Javaid, Hazel Inskip, Keith Godfrey, Christopher Bell, Karen Lillycrop, Cyrus Cooper & Nicholas Harvey, 2019, Journal of Bone and Mineral Research, 34(2), 231-240
DOI: 10.1002/jbmr.3603
Type: article