Research project

Functionalized Magnetic Resonance Beacons for Enhanced Spectroscopy and Imaging

Research groups:
Lead researchers:

Professor Malcolm Levitt
Research funder:

European Union
Status:

Not active

Project overview

Development and demonstration of molecular agents called functional magnetic resonance beacons (fMRBs). These agents support hyperpolarized spin order locked into long-lived states which may be converted into strong NMR signals upon activation by a physical, chemical, or biochemical signal.

Staff

Lead researchers

Professor Malcolm Levitt

Professor of Chemistry

Research interests

Magnetic Resonance
Endofullerenes

Connect with Malcolm

Email: mhl@soton.ac.uk

Collaborating research institutes, centres and groups

Magnetic Resonance

Our main focus is finding ways to extend the timescale over which magnetic resonance can be made.

Research outputs

Weak nuclear spin singlet relaxation mechanisms revealed by experiment and computation’

Boris Kharkov, Xueyou Duan, Jyrki JS Rantaharju, Mohamed Sabba, Malcolm H. Levitt, James W. Canary & Alexej Jerschow, 2022, Physical Chemistry Chemical Physics, 24(12), 7531-7538

DOI: 10.1039/D1CP05537B

Type: article

Direct production of a hyperpolarized metabolite on a microfluidic chip

Sylwia, Joanna Barker, Laurynas Dagys, William G Hale, Barbara H Ripka, James Eills, Manvendra Sharma, Malcolm H. Levitt & Marcel Utz, 2022, Analytical Chemistry, 94(7), 3260-3267

DOI: 10.1021/acs.analchem.1c05030

Type: article

Low-Frequency Excitation of Singlet-Triplet Transitions. Application to Nuclear Hyperpolarization

Laurynas Dagys, Christian Bengs & Malcolm H. Levitt, 2021, The Journal of Chemical Physics, 155(15), 1-9

DOI: 10.1063/5.0065863

Type: article

Generalised magnetisation-to-singlet-order transfer in nuclear magnetic resonance

Christian Bengs, Mohamed Sabba, Alexej Jerschow & Malcolm H. Levitt, 2020, Physical Chemistry Chemical Physics, 22(17), 9703-9712

DOI: 10.1039/D0CP00935K

Type: article

Fast destruction of singlet order in NMR experiments

Bogdan A. Rodin, Kirill F. Sheberstov, Alexey S. Kiryutin, Lynda J. Brown, Richard C.D. Brown, Mohamed Sabba, Malcolm H. Levitt, Alexandra V. Yurkovskaya & Konstantin L. Ivanov, 2019, The Journal of Chemical Physics, 151(23)

DOI: 10.1063/1.5131730

Type: article