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Research project

Exploitation of an ex-vivo disease model to characterise early events in retinal degeneration

Staff

Lead researchers

Dr Arjuna Ratnayaka

Associate Professor
Connect with Arjuna

Email: J.Ratnayaka@soton.ac.uk

Professor Andrew Lotery

Professor of Ophthalmology

Research interests

  • Ocular clinical trials
  • Age related macular degeneration
  • Central serous chorioretinopathy
Connect with Andrew

Email: A.J.Lotery@soton.ac.uk

Research outputs

Challenges in studying geographic atrophy (GA) age-related macular degeneration: the potential of a new mouse model with GA-like features
J. Arjuna Ratnayaka & Andrew Lotery, 2020, Neural Regeneration Research, 15(5), 863-864
DOI: 10.4103/1673-5374.268972
Type: article
Oxidative stress and dysfunctional intracellular traffic linked to an unhealthy diet results in impaired cargo transport in the Retinal Pigment Epithelium (RPE)
Eloise Keeling, David Chatelet, David Johnston, Anton Page, David Tumbarello, Andrew Lotery & J. Arjuna Ratnayaka, 2019, Molecular Nutrition & Food Research, 63(15)
DOI: 10.1002/mnfr.201800951
Type: article
Modelling Sorsby’s Fundus Dystrophy using patient-derived iPSC-RPE
Jennifer Dewing, David RG Christensen, Heidi Hongisto, Jennifer Scott, Ben Jenkins, Angela Cree, Heli Skottman, J. Arjuna Ratnayaka & Andrew Lotery, 2019, Investigative Ophthalmology & Visual Science, 60
Type: conference