Research project

eDropSeq

Project overview

Entrainment microfluidics for programming the high throughput co-encapsulation of single cells with RNA capture beads

Lead researcher

Associate Professor

Time-Resolved Structural Biology The emergence of serial crystallography brings many exciting possibilities for structural biology but also brings the challenge of preparing many thousands of sub-micron crystals. To address this, we are working with Ivo Tews and Allen Orville to develop high throughput droplet microfluidic systems. Here volumetric confinement of the phase diagram defines growth limits for producing monodisperse protein crystals. Beyond this, the microfluidic processors can be interfaced with the beam line to enable dynamic structural biology.

Connect with Jonathan

Email: J.J.West@soton.ac.uk