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Research project

CRUK - Targeting Myeloid Cells For Improved Antibody Immunotherapy - DRCRPG-May23/100001

Staff

Lead researchers

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering
  • Cancer Immunotherapy
Connect with Mark

Email: M.S.Cragg@soton.ac.uk

Other researchers

Dr Stephen Thirdborough

Senior Research Fellow
Connect with Stephen

Email: S.M.Thirdborough@soton.ac.uk

Professor Stephen Beers

Professor of Immunology & Immunotherapy
Connect with Stephen

Email: S.A.BEERS@soton.ac.uk

Professor Jon Strefford PhD

Head of School
Connect with Jon

Email: jcs@soton.ac.uk

Dr Matthew Carter

Senior Research Fellow

Research interests

  • Antibody Immunotherapy
  • Hypoxia
  • Molecular Cell Biology
Connect with Matthew

Email: M.J.Carter@soton.ac.uk

Professor Sean Lim

Professor of Haematology

Research interests

  • Identification of new therapeutic targets in lymphoma
  • Development of novel monoclonal antibody combination therapies for cancer
  • Understanding the determinants of an effective immune response in patients with lymphoma
Connect with Sean

Email: S.H.Lim@soton.ac.uk

Dr Jonathan West

Associate Professor

Research interests

  • Time-Resolved Structural Biology The emergence of serial crystallography brings many exciting possibilities for structural biology but also brings the challenge of preparing many thousands of sub-micron crystals. To address this, we are working with Ivo Tews and Allen Orville to develop high throughput droplet microfluidic systems. Here volumetric confinement of the phase diagram defines growth limits for producing monodisperse protein crystals. Beyond this, the microfluidic processors can be interfaced with the beam line to enable dynamic structural biology.
Connect with Jonathan

Email: J.J.West@soton.ac.uk

Dr Yury Bogdanov

Lecturer in Transgenic Technologies

Research interests

  • Tumour microenvironment
  • Neurotransmitters in Cancer
  • GABA and GABA receptors
Connect with Yury

Email: Y.D.Bogdanov@soton.ac.uk

Research outputs