Project overview
The aim of this project is to optimise and ultimately make the outputs of our Chlamydia-based Saturation mutagenesis system available to the research community through the Chlamydia Biobank. This includes desiging, executing and analysing the results of multiple sub-projects e.g. designing high throughput sequencing experiments to prove saturation mutagenesis and comparing this to the nanopore sequencing data we recently published; optimising the new expression control features to improve regulation of gene expression in C. trachomatis and improving transposon delivery vectors to increase transposon insertion frequency.
