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Research project

BB/D003318/1 - Nucleic Acid Sequence Recognition

Staff

Other researchers

Emeritus Professor Keith Fox

Research interests

  • DNA Interactions
  • Triplex DNA
  • Quadruplex DNA
Connect with Keith

Email: K.R.Fox@soton.ac.uk

Research outputs

Potent triple helix stabilization by 5?,3?-modified triplex-forming oligonucleotides
Nouha Ben Gaied, Zhengyun Zhao, Simon R. Gerrard, Keith R. Fox & Tom Brown, 2009, ChemBioChem, 10(11), 1839-1851
DOI: 10.1002/cbic.200900232
Type: article
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine
David A. Rusling, Guomei Peng, Natarajan Srinivasan, Keith R Fox & Tom Brown, 2009, Nucleic Acids Research, 37(4), 1288-1296
DOI: 10.1093/nar/gkn1060
Type: article
Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine
David A. Rusling, Victoria J. Broughton-Head, Alex Tuck, Hannah Khairallah, Sadie D. Osborne, Tom Brown & Keith R. Fox, 2008, Organic & Biomolecular Chemistry, 6(1), 122-129
DOI: 10.1039/b713088k
Type: article
2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices
Lavinia Brennan, Guomei Peng, Natarajan Srinivasan, Keith R. Fox & Tom Brown, 2007, Nucleosides, Nucleotides & Nucleic Acids, 26(10-12), 1283-1286
DOI: 10.1080/15257770701530525
Type: article
CG base pair recognition within DNA triple helices using N-methyl-3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues
Simon R. Gerrard, Srinivasan Natarajan, Keith R. Fox & Tom Brown, 2007, Nucleosides, Nucleotides & Nucleic Acids, 26(10-12), 1363-1367
DOI: 10.1080/15257770701533958
Type: article