Research project

A Tavassoli - CRUK Programme Foundation Award

Lead researchers:

Professor Ali Tavassoli
Research funder:

Cancer Research UK
Status:

Not active

Staff

Lead researchers

Professor Ali Tavassoli

Professor of Chemical Biology

Connect with Ali

Email: A.Tavassoli@soton.ac.uk

Research outputs

Identification and development of cyclic peptide inhibitors of Hypoxia Inducible Factors 1 and 2 that disrupt hypoxia-response signaling in cancer cells

Andrew T. Ball, Soran Mohammed, Cyrielle Doigneaux, Reece M. Gardner, James W. Easton, Steven Turner, Jonathan W. Essex, Garry Pairaudeau & Ali Tavassoli, 2024, Journal of the American Chemical Society

Type: article

Hypoxia drives the assembly of the multi-enzyme purinosome complex

Cyrielle Doigneaux, Anthony Pedley, Ishna N Mistry, Monika Papayova, Stephen Benkovic & Ali Tavassoli, 2020, The Journal of Biological Chemistry, 295(28), 9551-9566

DOI: 10.1074/jbc.RA119.012175

Type: article

Reprogramming the transcriptional response to hypoxia with a chromosomally encoded cyclic peptide HIF-1 inhibitor

Ishna Mistry & Ali Tavassoli, 2017, ACS Synthetic Biology, 6(3), 518-527

DOI: 10.1021/acssynbio.6b00219

Type: article