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Research project

A prospective multicentre study to determine the association between sarcopenia and grade 3 toxicity in people with metastatic breast cancer undergoing first line cytotoxic chemotherapy (CANDO-4)

Staff

Lead researchers

Dr Ellen Copson MB BS, PhD, FRCP

Professor
Connect with Ellen

Email: E.Copson@soton.ac.uk

Other researchers

Dr Stephen Wootton PhD FAfN OBE

Associate Professor
Connect with Stephen

Email: S.A.Wootton@soton.ac.uk

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Ramsey Cutress

Professor of Breast Surgery
Connect with Ramsey

Email: R.I.Cutress@soton.ac.uk

Dr Constantinos Savva MD, MSc, PhD, MRCP

Associate Professor of Medical Oncology

Research interests

  • The comprehensive evaluation of the immunometabolic phenotype of tumour microenvironment in breast cancer.
  • Investigation of the underlying biology and immunomodulatory effects of anti-PD1 and metformin combination using targeted transcriptomics and multiplex immunohistochemistry in a breast tumour murine model.
Connect with Constantinos

Email: C.Savva@soton.ac.uk

Research outputs