Research Institute

NiPPeR study

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Nutritional Intervention Preconception and during Pregnancy to maintain healthy glucosE metabolism and offspRing health (NiPPeR)

Part of Medicine

The NiPPeR study has involved 1,729 women from the UK, New Zealand and Singapore who were planning pregnancy. It is one of the largest international preconception randomised controlled trials of its type.

Child page cards

The NiPPeR study involves researchers in Southampton, Singapore and New Zealand from the EpiGen Global Research Consortium. They have trialled the use of a combination of nutrients and probiotics before and during pregnancy to improve the health of mothers and their children.

The NiPPeR multinational study is one the largest nutritional intervention studies in women during preconception and pregnancy.

  • 1729 women and their partners recruited
  • 585 NiPPeR babies delivered

Important insights have been emerging from the study. The EpiGen researchers continue to follow up the children, with an exciting new visit at age 6-8 years. We want to see if the benefits for the children are maintained into early school years and if better recommendations about the mother’s nutrition before and during pregnancy can support the children’s health, wellbeing and ability to learn.

Our teams have been busy following up the children and analysing the data and samples.

We thank our participants for all their contributions to the study and for their ongoing participation. Together we believe we can make a valuable positive impact on the health and wellbeing of mothers and the next generation.

 

Our partners


United Kingdom

Singapore

New Zealand

Related research institutes, centres and groups

Epigenetics

Our research utilises a multidisciplinary approach to explore the mechanisms underlying the interplay between environmental factors, genetic and epigenetic processes and their influence on disease risk across the lifecourse.