Dr Luke Hill

Dr Hill completed his undergraduate medical degree at the Brighton and Sussex Medical School in 2012, following award of an intercalated BSc in Infectious Diseases and Immunobiology from King’s College London in 2010. Following this he completed postgraduate medical training in the Wessex region, attaining a national training number in Medical Oncology in 2016 with specialty training positions at Southampton General Hospital and Queen Alexandra Hospital, Portsmouth.

In 2018 Dr Hill was awarded a CRUK Clinical Research Training Fellowship, and undertook a PhD in the laboratory of Professor Tim Elliott, in the Centre for Cancer Immunology at the University of Southampton. His project investigated CD8+ lymphocyte infiltrates in human oesophageal cancer, in collaboration with Professor Tim Underwood and his team, identifying an important population of CD8+ tissue resident memory cells. In 2022 he was awarded his PhD on returning to clinical training, and was appointed to an NIHR clinical lecturer position in Medical Oncology.

As a clinical lecturer, Dr Hill is an active member of the Innovation for Translation Research Group, co-led by Professor Underwood and Dr Zoe Walters where he is involved in a number of laboratory based projects, focusing on the immune microenvironment of oesophageal adenocarcinoma and gastrointestinal stromal tumours. A particular focus is the infiltration or exclusion of primary tumours, and metastases with effector CD8+ T lymphocytes. He is also involved in early phase clinical research, and has experience of this both at the Southampton NIHR Clinical Research Facility and as a visiting clinical research fellow at the Oxford Early Phase Clinical Trials Unit. He currently supports a portfolio of studies as a co-investigator, ranging from small molecule inhibitors, to personalised cancer vaccines and cellular therapies.