David Wilton

Publications

22 publications

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Tryptophan insertion mutagenesis of liver fatty acid-binding protein Acid-binding Protein

R.M. Hagan, J. Worner-Gibbs & D.C. Wilton, 2004, The Journal of Biological Chemistry, 280(3), 1782-1789

Type: article

Potentiation of tumor necrosis factor -induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome Proliferator-activated Receptor Activation

S. Beck, G. Lambeau, K. Scholz-Pedretti, M.H. Gelb, M.J.W. Janssen, S.H. Edwards, D.C. Wilton, J. Pfeilschifter & M. Kaszkin, 2003, The Journal of Biological Chemistry, 278(32), 29799-29812

DOI: 10.1074/jbc.M211763200

Type: article

Annexins and phospholipases

Andrew Buckland & David C. Wilton, 2003

Type: bookChapter

Effect of tryptophan insertions on the properties of the human group IIA phospholipase A2: mutagesesis produces an enzyme with characteristics similar to those of the human group V phospholipase A2

S.A. Beers, A.G. Buckland, N. Giles, M.H. Gelb & D.C. Wilton, 2003, Biochemistry, 42(24), 7326-7338

DOI: 10.1021/bi0343222

Type: article

The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A(2) at 1.5 angstrom resolution provides an insight into the catalytic mechanism

Suzanne H. Edwards, Darren Thompson, Sharon F. Baker, Stephen P. Wood & David C. Wilton, 2002, Biochemistry, 41(52), 15468-15476

DOI: 10.1021/bi020485z

Type: article

Effect of charge reversal mutations on the ligand- and membrane-binding properties of liver fatty acid-binding protein

J.K. Davies, R.M. Hagan & D.C. Wilton, 2002, The Journal of Biological Chemistry, 277(50), 48395-48402

DOI: 10.1074/jbc.M208141200

Type: article

The effect of charge reversal mutations in the ?-helical region of liver fatty acid binding protein on the binding of fatty-acyl CoAs, lysophospholipids and bile acids

Robert Hagan, Joanna K. Davies & David C. Wilton, 2002, Molecular and Cellular Biochemistry, 239(1/2), 55-60

DOI: 10.1023/A:1020562808304

Type: article

The antibacterial properties of secreted phospholipases A(2) - A major physiological role for the group IIA enzyme that depends on the very high pI of the enzyme to allow penetration of the bacterial cell wall

S.A. Beers, A.G. Buckland, R.S. Koduri, W. Cho, M.H. Gelb & D.C. Wilton, 2001, The Journal of Biological Chemistry, 277(3), 1788-1793

DOI: 10.1074/jbc.M109777200

Type: article

A comparison of the molecular species compositions of mammalian lung surfactant phospholipids

Anthony D. Postle, Emma L. Heeley & David C. Wilton, 2001, Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, 129(1), 65-73

DOI: 10.1016/S1095-6433(01)00306-3

Type: article

The antibacterial properties of secreted phospholipases A2

Andrew G. Buckland & David C. Wilton, 2000, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1488(1-2), 71-82

DOI: 10.1016/S1388-1981(00)00111-6

Type: article

Emeritus Professor David Wilton

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