Roxana-Octavia Carare

Research interests

Causes and new therapeutic strategies for dementias and other neurodegenerative diseases

New early diagnostic measures in dementia based on biomarkers from the nose

Drug delivery to the brain

Accepting applications from PhD students.

Research

Research groups

Member of:

Research interests

Causes and new therapeutic strategies for dementias and other neurodegenerative diseases
New early diagnostic measures in dementia based on biomarkers from the nose
Drug delivery to the brain

Research projects

Active projects

Macrophages in neurological diseases

Researchers:

Professor Roxi Carare

Brain Clearance: A Translational Approach Towards Understanding and Therapy

Researchers:

Professor Roxi Carare

TIMP-3 Proteinopathy: A novel mechanism in age-associated neurodegenerative diseases

Researchers:

Professor Roxi Carare

Doctor Jennifer Dewing

Sponsor: Alzheimers Society

Prognostic Nasal Biomarkers In Dementia With Lewy Bodies

Researchers:

Professor Roxi Carare

Mr Rami Salib

Holistic Optical Biomarkers for Early Differential Dementia Diagnosis (HOpE)

Researchers:

Professor Sumeet Mahajan

Professor Roxi Carare

Professor Amritpal Mudher ,

Professor Jessica Teeling ,

Professor Mahesan Niranjan ,

Doctor Jonathan Swann

Completed projects

Carare - Royal Society - LOX as therapeutic target to improve IPAD - May 18

Researchers:

Professor Roxi Carare

Sponsor: Royal Society

R Carare - Physiology of Perivascular drainage of the brain and how it is affected by advancing age

Researchers:

Professor Roxi Carare

Professor James Nicoll

Sponsor: Biotechnology & Biological Sciences Research Council

Dr R Carare: Symposium on dementia for early career researchers as a satellite to Vas-Cog conference in Japan

Researchers:

Professor Roxi Carare

Sponsor: SASAKAWA Foundation

AAV9 distribution in the brain

Researchers:

Professor Roxi Carare

Sponsor: Alcyone Lifesciences Inc.

Noradrenergic regulation of amyloid clearance in AD

Researchers:

Professor Roxi Carare

Sponsor: BrightFocus Foundation

Exosomes in neurological diseases

Researchers:

Professor Roxi Carare

Dr R Carare: Age-related changes in the basement membrane of cerebral blood vessels: implications for Alzheimer's

Researchers:

Professor Roxi Carare

Professor James Nicoll

Sponsor: Alzheimers Research UK

Vascular dementia: failure of elimination of waste from the brain

Researchers:

Professor Roxi Carare

Sponsor: Stroke Association

R Carare: Confocal laser scanning microscope for dementia researchers in Southampton

Researchers:

Professor Roxi Carare

Sponsor: Alzheimers Research UK

R Carare BNS: White matter hyperintensitites in dementia, investigating impaired drainage of interstitial fluid

Researchers:

Professor Roxi Carare

Sponsor: British Neuropathological Society

Dr R. Carare: Changes in the perivascular pathways for the elimination of amyloid from the ageing brains. (Linked to 512536101)

Researchers:

Professor Roxi Carare

Sponsor: Rosetrees Trust

R Carare: Anatomy of the Neurovascular Unit and Glia limitans interface

Researchers:

Professor Roxi Carare

Sponsor: inviCRO LLC

R Carare - Effect of prenatal high fat exposure on cerebrovascular basement membranes, implications for Alzheimer's Disease

Researchers:

Professor Roxi Carare

Sponsor: Protea Biosciences Inc

Dr R. Carare: Collaboration - Kyoto University

Researchers:

Professor Roxi Carare

Sponsor: SASAKAWA Foundation

SCD in neurological diseases

Researchers:

Professor Roxi Carare

Confocal laser scanning microscope for dementia researchers

Researchers:

Professor Roxi Carare

Professor Delphine Boche ,

Professor Andrew Lotery ,

Doctor Arjuna Ratnayaka ,

Doctor David Johnston ,

Professor James Nicoll ,

Professor Amritpal Mudher

Adrenergic innervation: a target for Alzheimer's disease

Researchers:

Professor Roxi Carare

Sponsor: Alzheimers Research UK

Dr R Carare 2006B

Researchers:

Professor Roxi Carare

Emeritus Professor Hugh Perry

Sponsor: Alzheimers Research UK

Carare - British Neuropathological Society - Small Grants Award

Researchers:

Professor Roxi Carare

Sponsor: British Neuropathological Society

H2020-LC-MG-2018-TUBE

Researchers:

Professor Roxi Carare

Sponsor: European Union

Dr Hawkes: Drainage failure of fluid and solutes from the brain in Cerebral Amyloid Angiopathy: A prelude to Alzheimer's disease

Researchers:

Professor Roxi Carare

Sponsor: Alzheimers Research UK

Dr R. Carare: Age-related changes in VBM

Researchers:

Professor Roxi Carare

Professor James Nicoll

Sponsor: Wessex Medical Research

Anti-Tau immunization in Alzheimer's disease

Researchers:

Professor Roxi Carare

CA-mitochondria-Alzheimer's disese

Researchers:

Professor Roxi Carare

Sponsor: Temple University

R Carare OU: Targeting perivascular innervation and vascular tone for improved clearnace of Beta amyloid from the brain

Researchers:

Professor Roxi Carare

Sponsor: Alzheimers Research UK

Immunization-neurodegenerative diseases

Researchers:

Professor Roxi Carare

Professor James Nicoll

Dr. Carare: Changes in Leptomeningeal Arteries

Researchers:

Professor Roxi Carare

Professor Jessica Teeling ,

Professor James Nicoll

Sponsor: Alzheimers Research UK

R Carare Rosetrees: The role of maternal high fat in predisposing the offspring to Alzheimer's Disease

Researchers:

Professor Roxi Carare

Doctor Felino Cagampang

Sponsor: Rosetrees Trust

Cerebral Smooth Muscle Mitochondria As Key For The Treatment Of CAA

Researchers:

Professor Roxi Carare

Sponsor: National Institutes of Health

Cortical Disarray Measurement (CDM) in the early diagnosis of dementia

Researchers:

Professor Roxi Carare

Boche - ARUK - 3D imaging for Life Sciences - (April 18)

Researchers:

Professor Delphine Boche

Professor Roxi Carare

Professor James Nicoll ,

Doctor Felino Cagampang ,

Doctor Arjuna Ratnayaka ,

Doctor Sandrine Willaime-Morawek

Sponsor: Alzheimers Research UK

In vivo analysis of the Intramural Periarterial Drainage pathway connecting the brain to the immune system

Researchers:

Professor Roxi Carare

Sponsor: Alzheimers Research UK

Your Brain Explained

Researchers:

Professor Kath Woods-Townsend ,

Professor Roxi Carare

Novel nasal biomarkers for Alzheimer's Dementia

Researchers:

Mr Rami Salib

Professor Roxi Carare

Sponsor: ENTUK Foundation

Biography

Roxana Carare qualified in Medicine in Bucharest in 1994. During her basic clinical training, she became fascinated by anatomy and completed her PhD in neuropathology in 2006, in the University of Southampton, UK. The main international recognition for Roxana Carare has come from the interdisciplinary research she leads, relevant to drug delivery to the brain and to the causes and new treatments for Alzheimer's disease, with over 120 peer reviewed publications in the field. Roxana is a member of the UK Medical Research Council Dementia Platform UK Vascular Experimental Medicine committee and the UK government advisory committee for the effects of pollution on the brain, has served as the only European member of the American NIH strategy committee for funding in dementia. Roxana has won prestigious awards, including a Dementia Research Leader award from Alzheimer’s Society UK. Roxana has served as Co-Chair for The International Alliance of Women Alzheimer's Researchers in Alzheimer’s Association, Vice-Chair of the Vascular Professional Interest Area of Alzheimer’s Association, co-leads the Scientific Committee for Vas-Cog, Secretary of the British Neuropathological Society, member of the scientific committee of the Rainwater Foundation, serves as an expert for several international research funding boards. Roxana is a Visiting Professor in the University of Medicine, Pharmacy, Science and Technology Targu Mures- Romania where she has co-founded the British-Romanian Academic Institute of Neuroscience.

Prizes

Dementia Leader Award, Alzheimer’s Society (2015)
Influential Woman of the Year (2016)
Dementia Leader Award, Alzheimer’s Society (2015)
Influential Woman of the Year (2016)

Professor Roxi Carare

Research interests

Research

Research groups

Research interests

Research projects

Active projects

Completed projects

Publications

External roles and responsibilities

Biography

Prizes