Module overview
Applied Knowledge A will enable you to understand key physiological, anatomical & biochemical concepts and principles that you can apply in clinical scenarios.
You will study: key features and stages in the human life cycle; the structure and function of biological molecules and the principles of metabolism; the structure and function of cells and tissues; anatomy; nutrition and the digestive system; enzymology and energetics; medical microbiology and immunology; the organisation of healthcare; numerical calculations related to clinical care.
Aims and Objectives
Learning Outcomes
Having successfully completed this module you will be able to:
- Describe key features and stages in the human life cycle
- Explain the process of digestion and absorption of macronutrients
- Identify the phases of the cell cycle and causes and implications of its disruption
- Demonstrate an understanding of cell biology
- Describe the structure and characteristics of biological molecules
- Demonstrate a sound understanding of the principles of metabolism
- Calculate the number of moles or grams of a substance and the molarity of various solutions
- Describe the features of disease-causing micro-organisms and the consequences of infection
- Demonstrate a sound understanding of ionisation, kinetics and enzymology
- Explain the key features of a balanced diet
- Identify anatomical structures using appropriate terminology
- Demonstrate a broad overview of the organisation, funding and quality assurance of health care
- Describe the principles of immunology
- Accurately perform numerical conversions and calculations without the use of a calculator
- Explain the structural organisation of the human body
- Accurately use scientific notations and prefixes
Syllabus
In order to meet the learning outcomes, the syllabus will contain teaching in the following areas:
• The Human Life Cycle
Stages of life, factors affecting quality and longevity of life. Types of growth and growth disorders. Bone growth and maintenance. Use of growth charts. Cause and effect of ageing of tissues and systems. Main theories of ageing
• Structural organisation of the body - Key features of cells, tissues and systems in the body and the principle of complementarity of structure and function.
• Cell biology - Structure and function of cell organelles and cytoskeletal elements. Consequences of organelle dysfunction and cellular response to stress. Mitosis, meiosis and gametogenesis. DNA replication and protein synthesis. The cell cycle and its regulation.
• Membranes - Structure and function of membranes, associated membrane specialisations and cell junctions. Chemical and electrical gradients across the cell membrane and the basis of the resting membrane potential and membrane transport.
• Medical microbiology - Microorganisms of relevance to medicine. Structure and characteristics of bacteria and viruses. Aspects of selected bacterial and viral diseases including the use of antibiotics and antivirals.
• The human body’s defences - Specific and non-specific defences. Types of immunity and key features of the immune system. Characteristics and examples of autoimmune diseases and hypersensitivity reactions.
• Anatomy - Anatomical terminology of regions of the body, with a focus on the limbs, thorax and abdomen
• Structure and characteristics of biological molecules - Structure, bonding and organisation of proteins, lipids, carbohydrates and nucleic acids. The role of molecules in health and disease.
• Nutrition and diet - The role of macro- and micronutrients in a balanced diet and deficiency disorders.
• Digestion and absorption of key macromolecules - Chemical and mechanical digestion and absorption of proteins, lipids and carbohydrates. Conditions of maldigestion and malabsorption.
• Principles of isomerism, ionisation, kinetics and enzymology -
• Principles of energetics, metabolism and metabolic pathways - Key aspects of metabolism. Overview of key metabolic pathways, their integration and control.
Learning and Teaching
Teaching and learning methods
The module will be taught through a range of learning and teaching strategies which will include:
• Lectures
• Tutorials
• Practical sessions
• Guided self-study
• Clinical scenarios
• Group work
• eLearning
Type | Hours |
---|---|
Revision | 69 |
Lecture | 88 |
Follow-up work | 50 |
Wider reading or practice | 50 |
Practical classes and workshops | 22 |
Tutorial | 33 |
Preparation for scheduled sessions | 50 |
Total study time | 362 |
Resources & Reading list
General Resources
Reading List. The full reading list for Applied Knowledge A is available on the Library Online Reading List at https://soton.rl.talis.com/
Assessment
Formative
This is how we’ll give you feedback as you are learning. It is not a formal test or exam.
Exam
- Assessment Type: Formative
- Feedback: General feedback is provided to all students. One-to-one feedback meetings are available for all students, and will be offered to failed students before the summative.
- Final Assessment:
- Group Work: No
Summative
This is how we’ll formally assess what you have learned in this module.
Method | Percentage contribution |
---|---|
Exam | 100% |
Referral
This is how we’ll assess you if you don’t meet the criteria to pass this module.
Method | Percentage contribution |
---|---|
Exam | 100% |
Repeat Information
Repeat type: External