Module overview
Linked modules
Pre-requisites: CHEM3038 or CHEM6095
Aims and Objectives
Learning Outcomes
Learning Outcomes
Having successfully completed this module you will be able to:
- Highlight key applications of synthetic methods to understanding the biological function of carbohydrate based biomolecules.
- Describe essential techniques employed in chemical biology for the synthesis, characterisation and engineering of biomolecules.
- Discuss the mode of action of important classes of chemical probes.
- Understand the importance of chemical biology methods for the discovery of novel drugs to treat diseases.
- Draw the structure of common biorthogonal reagents and the molecular mechanisms (curly arrows) underlying protein labelling.
Syllabus
•Proteins, nucleic acids and their characterisation
•Protein engineering, directed evolution and synthetic biologicals
•Chemical probes to study biomolecules: design and mode of action
•Bioconjugation reactions and labelling of peptides and proteins
•Understanding glycobiology with chemistry
Learning and Teaching
Teaching and learning methods
Lectures, workshops
| Type | Hours |
|---|---|
| Revision | 44 |
| Wider reading or practice | 44 |
| Lecture | 24 |
| Workshops | 6 |
| Preparation for scheduled sessions | 6 |
| Total study time | 124 |
Assessment
Summative
This is how we’ll formally assess what you have learned in this module.
| Method | Percentage contribution |
|---|---|
| Final Assessment | 100% |
Repeat Information
Repeat type: Internal & External