Module overview
Aims and Objectives
Learning Outcomes
Knowledge and Understanding
Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:
- Describe the structure of nucleic acids and explain how DNA is replicated, transcribed and translated into proteins.
- Describe the secondary, tertiary and quaternary structures of proteins including explanation of the forces involved in forming and maintaining such structures.
- Describe the structures and properties of the amino acids found in proteins including examples of post-translational modifications to their structure.
- Describe the structure of membranes and the structures/functions of proteins found in membranes.
- Explain the Michaelis-Menten model of enzyme kinetics, including the effects of inhibitors, substrate concentration, temperature, pH and allosteric regulators on enzyme activity.
- Define a plasmid and explain the use of restriction enzymes in creating recombinant DNA for use in molecular biology/biotechnology.
Subject Specific Practical Skills
Having successfully completed this module you will be able to:
- Know how to perform fundamental molecular laboratory techniques such as running gels, column chromatography and measuring absorbances.
Syllabus
Learning and Teaching
Teaching and learning methods
Type | Hours |
---|---|
Independent Study | 121 |
Lecture | 20 |
Practical classes and workshops | 9 |
Total study time | 150 |
Resources & Reading list
General Resources
Blackboard site. Additional supporting material for this module can be found on the Blackboard module page. This includes access to virtual practicals.
Textbooks
Roger Miesfeld and Megan McEvoy (2017). Biochemistry. W. W. Norton & Company.
Gerhard Meisenberg & William H. Simmons (2016). Principles of Medical Biochemistry. Elsevier Health Sciences.
Despo Papachristodoulou, Alison Snape, William H. Elliott and Daphne C. Elliott (2018). Biochemistry and Molecular Biology. Oxford University Press.
Assessment
Assessment strategy
Assessment will be by an end of module computer based multiple choice exam. Practical write-ups will also be be assessed.Summative
This is how we’ll formally assess what you have learned in this module.
Method | Percentage contribution |
---|---|
Final Assessment | 75% |
Practical write-ups | 25% |
Referral
This is how we’ll assess you if you don’t meet the criteria to pass this module.
Method | Percentage contribution |
---|---|
Final Assessment | 100% |