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Research project

Simpson - Diversity in blood flow control to the brain: moving from individualised modelling towards personalised treatment of the injured brain

Staff

Lead researchers

Professor David Simpson

Prof of Biomedical Signal Processing

Research interests

  • His research interests are in biomedical signal processing with applications in neurophysiology and cardio-vascular and cerebro-vascular control. Specific topics are:
  • Blood flow control in the brain (how does the brain regulate is own blood supply and how to detect impairment of this function).
  • Auditory evoked potentials (methods to detect the small electrical responses of the brain to auditory stimulation for the assessment of various hearing disorders).
Connect with David

Email: ds@isvr.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Assessing cerebral blood flow control from variability in blood pressure and arterial CO2 levels
Dragana Nikolic, Anthony Birch, Ronney Panerai & David Simpson, 2015
DOI: 10.1109/EMBC.2015.7318725
Type: conference
Rapid pressure-to-flow dynamics of cerebral autoregulation induced by instantaneous changes of arterial CO2
Jia Liu, David M. Simpson, Hesam Kouchakpour, Ronney B. Panerai, Jie Chen, Shan Gao, Pandeng Zhang & Xinyu Wu, 2014, Medical Engineering & Physics, 36(12), 1636-1643
DOI: 10.1016/j.medengphy.2014.09.005
Type: article
Optimising the assessment of cerebral autoregulation from black box models
N. Angarita-Jaimes, H. Kouchakpour, J. Liu, R.B. Panerai & D.M. Simpson, 2014, Medical Engineering & Physics, 36(5), 607-612
DOI: 10.1016/j.medengphy.2013.12.012
Type: article
Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure–flow relation: the CARNet study
Aisha S.S. Meel-van den Abeelen, David M. Simpson, Lotte J.Y. Wang, Cornelis H. Slump, Rong Zhang, Takashi Tarumi, Caroline A. Rickards, Stephen Payne, Georgios D. Mitsis, Kyriaki Kostoglou, Vasilis Marmarelis, Dae Shin, Yu-Chieh Tzeng, Philip N. Ainslie, Erik Gommer, Martin Müller, Alexander C. Dorado, Peter Smielewski, Bernardo Yelicich, Corina Puppo, Xiuyun Liu, Marek Czosnyka, Cheng-Yen Wang, Vera Novak, Ronney B. Panerai & Jurgen A.H.R. Claassen, 2014, Medical Engineering & Physics, 36(5), 620-627
DOI: 10.1016/j.medengphy.2014.02.002
Type: article
Low-frequency heart rate variability is related to the breath-to-breath variability in the respiratory pattern
Alessandro Beda, David M. Simpson, Nadja C. Carvalho & Alysson Roncally S. Carvalho, 2013, Psychophysiology, 51(2), 197-205
DOI: 10.1111/psyp.12163
Type: article